Advanced Science, EarlyView.This work identifies M1 macrophage‐mediated inflammation as a key driver of BMSC senescence and bone microstructural deterioration at the enthesis. A tissue‐adhesive hydrogel delivering senomorphic small extracellular vesicles suppresses this inflammatory‐senescent cascade and enhances BMSC resilience by inhibiting the cGAS‐STING‐NF‐κB pathway.
Lingzhi Kong +8 more
wiley +1 more source
Integrating Eye Tracking and Inertial Sensing for Enhanced Freezing of Gait Detection in Parkinson's Disease. [PDF]
Eur J NeurosciPulliam CL, Chen J, Liao JY.
europepmc +1 more source
Bioinspired Morphology‐Decoupled Soft Gripper with Enhanced Bidirectional Grasping Capability
Advanced Science, EarlyView.Inspired by biological predation, a novel gripper decouples cross‐modal grasping via dual morphological configurations. Synergistically integrating hybrid rigid and soft coupled fingers with a metamaterial palm, the system performs active compliant grasping for static objects and passive cage capture for dynamic targets.
Yedong Huang +4 more
wiley +1 more source
Efficient and Scalable Tuning of Continuous Impedance Control for Powered Knee Prostheses. [PDF]
IEEE Robot Autom LettHong W, Naseri A, Huang HH.
europepmc +1 more source
Flexible IMU Sensor Array For 3D Colonoscope Shape Reconstruction and AI‐Based Loop Detection
Advanced Science, EarlyView.We propose a sensing platform for 3D visualization of the colonoscope combined with artificial intelligence (AI)‐based loop detection. The system consists of an array of 15 inertial measurement units (IMUs) mounted on a flexible printed circuit board that can be retrofitted into the instrument channel of conventional colonoscopes.
Tuukka Panula +3 more
wiley +1 more source
Bone morphology and alignment features are associated with knee kinematics in healthy individuals: A scoping review. [PDF]
J Exp OrthopTeule E +3 more
europepmc +1 more source
Advanced Science, EarlyView.A rotational energy harvesting device that successfully reconciles high power density with mechanical durability through a hybrid sliding‐and‐bouncing kinematic mechanism is reported. The success reported in our paper includes addressing a dilemma where enhanced electrical output comes at the cost of increased friction and wear, limiting the practical ...
Yihong Lin +12 more
wiley +1 more source
Concurrent validation of OpenCap for identifying ACL re-injury risk factors during a drop jump test in a healthy cohort. [PDF]
Sci RepFärber B, Horsak B, Paternoster FK.
europepmc +1 more source
Advanced Science, EarlyView.Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu +15 more
wiley +1 more source
Effect of femoral component design and quadriceps load on patellofemoral kinematics after total knee arthroplasty: an in vitro cadaveric study. [PDF]
Knee Surg Relat ResMaioli V +6 more
europepmc +1 more source