Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat +6 more
wiley +1 more source
Understanding human arm stiffness modulation in overground pHRI: The roles of kinematics, perturbation, and trunk sway. [PDF]
Mohammadi Beirami M +3 more
europepmc +1 more source
Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale +6 more
wiley +1 more source
The role of skin mechanics in contact force variation under different friction conditions. [PDF]
Devecioğlu İ +7 more
europepmc +1 more source
A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies +14 more
wiley +1 more source
Validity, Reliability and Interpretability of an IMU-Based System to Measure 3D Lower Limb Kinematics of Patients with Heterogeneous Gait Disorders. [PDF]
Carcreff L +5 more
europepmc +1 more source
Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin +2 more
wiley +1 more source
Concurrent validation of a novel intraoperative navigation platform for total knee arthroplasty. [PDF]
Demeulenaere M +6 more
europepmc +1 more source
Hierarchical Artificial Muscle with Nonlinear Elasticity for Antagonistic and Cyclic Robotics
We construct hierarchical muscles by plying nylon fibers around a heating wire. The hierarchical muscle shows a J‐shaped passive curve, which shows benefit in antagonistic muscle pair and work accumulation mechanism. We also develop a computational, first‐principle model to understand the physics of both active actuation stroke and passive J‐curve ...
Samuel Tsai +15 more
wiley +1 more source
ULTRA-MoCap: A Multimodal IMU and sEMG Dataset for Upper Body Joint Kinematics Analysis. [PDF]
Fritsche O +8 more
europepmc +1 more source

