Cytoskeletal Dynamics and Molecular Motor Dysfunction in Psychiatric Disorders: Insights from Schizophrenia and Autism Spectrum Disorder. [PDF]
Nakamura K +5 more
europepmc +1 more source
MiR-153-3p Suppresses Cell Proliferation, Invasion and Glycolysis of Thyroid Cancer Through Inhibiting E3F3 Expression [Retraction]. [PDF]
europepmc +1 more source
<i>KIF5C</i>-Related Neurodevelopmental Disorder: Three New Cases and Additional Neuroradiologic Insights. [PDF]
Politano D +10 more
europepmc +1 more source
KIF20A promotes cervical cancer progression by interacting with CLIP1. [PDF]
Ma X +6 more
europepmc +1 more source
A biochemical probe for microtubule lattice integrity uncovers motor-caused lattice damage
Egoldt C +6 more
europepmc +1 more source
Regulation of microtubule abundance and minus end dynamics by Katanin, CAMSAPs, WDR47 and kinesin-13
Rai D +7 more
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Structures of kinesin and kinesin–microtubule interactions
Current Opinion in Cell Biology, 1999Several X-ray crystal structures of kinesin motor domains have recently been solved at high resolution ( approximately 0.2-0.3 nm), in both their monomeric and dimeric states. They show the folding of the polypeptide chain and different arrangements of subunits in the dimer.
Mandelkow, Eckhard, Hoenger, Andreas
openaire +3 more sources
Kinesin-5 inhibitor resistance is driven by kinesin-12 [PDF]
The microtubule (MT) cytoskeleton bipolarizes at the onset of mitosis to form the spindle. In animal cells, the kinesin-5 Eg5 primarily drives this reorganization by actively sliding MTs apart. Its primacy during spindle assembly renders Eg5 essential for mitotic progression, demonstrated by the lethal effects of kinesin-5/Eg5 inhibitors (K5Is ...
Yan Guo, Stephen R Norris, Ohi Ryoma
exaly +3 more sources
Kinesin-1 is a single-molecule walking machine, driven by ATP turnover. Recent optical trapping experiments show that pulling backwards on a walking kinesin-1 molecule causes the mechanical walking action to reverse, while the coupled chemical cycle of ATP turnover continues, apparently, to run forwards -- kinesin can moonwalk.
Nicholas J, Carter, Robert A, Cross
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