Results 81 to 90 of about 264,378 (313)

Kinetic Approaches to Measuring Peroxiredoxin Reactivity

Molecules and Cells, 2016
Peroxiredoxins are ubiquitous thiol proteins that catalyse the breakdown of peroxides and regulate redox activity in the cell. Kinetic analysis of their reactions is required in order to identify substrate preferences, to understand how molecular structure affects activity and to establish their physiological functions. Various approaches can be taken,
Winterbourn, Christine C., Peskin, Alexander V.   +1 more
openaire   +3 more sources

First remote sensing measurements of ClOOCl along with ClO and ClONO2 in activated and deactivated Arctic vortex conditions using new ClOOCl IR absorption cross sections [PDF]

, 2009
. Active chlorine species play a dominant role in the catalytic destruction of stratospheric ozone in the polar vortices during the late winter and early spring seasons. Recently, the correct understanding of the ClO dimer cycle was challenged by the
Wagner, Georg, G. Wagner, Wetzel, G., Birk, Manfred, Kirner, Oliver, G. Maucher, Oelhaf, Hermann, Engel, A., Kleinert, Anne, Oelhaf, H., Maucher, Guido, H. Oelhaf, Friedl-Vallon, F., Kirner, O., G. Wetzel, Wagner, G., Birk, M., Fischer, H., Engel, Andreas, A. Kleinert, Friedl-Vallon, Felix, F. Friedl-Vallon, A. Engel, H. Fischer, Kleinert, A., Wetzel, Gerald, Ruhnke, Roland, Maucher, G., Fischer, Herbert, O. Kirner, Ruhnke, R., M. Birk, R. Ruhnke   +32 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Isotopic Measurement of Glucose and Lactate Kinetics

Annals of Medicine, 1990
A variety of isotopic tracers can be used to quantitate glucose kinetics in vivo. Using the standard approach to calculate the rate of appearance (Ra) of glucose from kinetic data, different rates of Ra glucose are obtained depending on the nature and position of the label in glucose.
openaire   +2 more sources

Kinetic measurements of E-selectin/carbohydrate ligand interactions on the cell surface

, 2001
The kinetic measurements of E-selectin/carbohydrate ligand interactions were performed on the cell surface. The micropipette method was applied to the study of E-selectin/carbohydrate ligand interactions and extended from adhesion kinetic measurements to
龙勉, Huang KS, Zhao H
core  

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Hohenpeissenberg Photochemical Experiment (HOPE 2000) : measurements and photostationary state calculations of OH and peroxy radicals

, 2002
Measurements of OH, total peroxy radicals, non-methane hydrocarbons (NMHCs) and various other trace gases were made at the Meteorological Observatory Hohenpeissenberg in June 2000. The data from an intensive measurement period characterised by high solar
Gilge, Stefan, Bingemer, Heinz, Gilge, S., Plass-Dülmer, C., Bingemer, H., C. Plass-Dülmer, H. Bingemer, Berresheim, Harald, Handisides, G. M., G. M. Handisides, S. Gilge, Berresheim, H., Plaß-Dülmer, Christian, Handisides, Graeme M., H. Berresheim   +14 more
core   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Regime mapping and the role of the intermediate region in wall-coated microreactors [PDF]

, 2013
Operation of a wall-coated microreactor can occur in several mass transfer-reaction regimes. We define these regimes analytically in several planes of a multi-parametric map, taking into account the different degrees of concentration profile development,
A. E. Rodrigues, Rodrigues, A.E., Cardoso, S.S.S., J. P. Lopes, M. A. Alves, Lopes, J.P., S. S. S. Cardoso, Oliveira, Monica, Alves, M.A., M. S. N. Oliveira   +9 more
core   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source