Results 81 to 90 of about 2,148,955 (257)

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Parameter balancing for kinetic metabolic models

, 2019
Parameter balancing is a computational method for obtaining consistent parameter sets for kinetic metabolic models. Experimentally measured values, when inserted into models directly, would be likely to yield incomplete and inconsistent parameter sets ...
Lubitz, Timo, Liebermeister, Wolfram
core   +1 more source

Prototype of a Spring-Loaded Module for Axillary Crutches

Sensors
Axillary crutches assist people with lower limb injuries but can lead to upper limb strain with extended use. Spring-loaded crutches offer a potential solution, yet they are rarely tested in clinical settings.
Dalia Danely Méndez-Gómez, Arturo Minor-Martínez, Salvador Montoya-Alvarez, Fernando Pérez-Escamirosa, Jessica Cantillo-Negrete   +4 more
doaj   +1 more source

Parameter estimates of the within-host pharmacokinetic–viral kinetic model.

, 2023
Parameter estimates of the within-host pharmacokinetic–viral kinetic model.
David P. Durham (10947466), Jason Asher (8496111), Diana Y. Wong (14341733), Barry Clinch (5863964), Klaus Kuhlbusch (5148368), Annabelle Lemenuel-Diot (14341724), Carlos J. Arguello (1711786), Luis Mier-y-Teran-Romero (4220464), Jean-Eric Charoin (14341736), Matthew Clay (14341727), Sebastien Jolivet (14341730)   +10 more
core   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau, Marie Bruguet, Irina Viakhireva‐Dovganyuk, François‐Mathias Merrien, Denis Marechal, Aurore Jourdain, Philippe Goas, Jordan Coris, Julien Asselineau, Maëlys Consigny, Gérald Le Gac, Serge Timsit   +11 more
wiley   +1 more source

Propagation of Blood Function Errors to the Estimates of Kinetic Parameters with Dynamic PET

International Journal of Biomedical Imaging, 2011
Dynamic PET, in contrast to static PET, can identify temporal variations in the radiotracer concentration. Mathematical modeling of the tissue of interest in dynamic PET can be simplified using compartment models as a linear system where the time ...
Yafang Cheng, İmam Şamil Yetik
doaj   +1 more source

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias, Federica Avantaggiato, Gianni Pezzoli, Andrea Canessa   +3 more
wiley   +1 more source

Kinetic Parameter Studies Of Activated Sludge Process For Anaerobic Pre-Treated Palm Oil Mill Effluent [TD756.45. A286 2007 f rb]. [PDF]

, 2007
Kajian yang dilaporkan adalah mengenai penilaian parameter kinetik proses enapcemar teraktif bagi mengolah effluen dari kilang kelapa sawit. Hipotesis kajian ini adalah parameter kinetik yang dikaji boleh digunapakai untuk menilai keupayaan proses ...
Che Ibrahim, Ahmad Kamarulnajuib
core   +1 more source

Revisiting Stability Criteria in Ball‐Milled High‐Entropy Alloys: Do Hume–Rothery and Thermodynamic Rules Equally Apply?

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
The stability criteria affecting the formation of high‐entropy alloys, particularly focusing in supersaturated solid solutions produced by mechanical alloying, are analyzed. Criteria based on Hume–Rothery rules are distinguished from those derived from thermodynamic relations. The formers are generally applicable to mechanically alloyed samples.
Javier S. Blázquez, Alejandro F. Manchón‐Gordón, Antonio Vidal‐Crespo, Rafael Caballero‐Flores, Jhon J. Ipus, Clara F. Conde   +5 more
wiley   +1 more source

Cloning and molecular characterization of ant(9)-If: a novel aminoglycoside adenylyltransferase gene conferring resistance to spectinomycin

Frontiers in Microbiology
BackgroundEnterococcus is an opportunistic pathogen with the potential to induce infections in both animals and humans. The antimicrobial resistance mechanism of Enterococcus is highly complex, leading to challenges in the clinical treatment of ...
Susu Chen, Huiqin Liu, Jie Yang, Yali Huang, Xiuxiu Wang, Junjun Wang, Lulu Huang, Xiaolan Wu, Junwan Lu, Qiyu Bao, Qiyu Bao, You Zhou, Teng Xu, Hongqin Zhang   +13 more
doaj   +1 more source