Results 111 to 120 of about 7,018 (220)

Müller cell markers in aqueous humor of patients with type-2 macular telangiectasia

Indian Journal of Ophthalmology
Purpose: To investigate the pathogenesis of type-2 macular telangiectasia (MacTel) by comparing the levels of glial fibrillary acidic protein (GFAP), aquaporin-4 (AQP4), and K+ inwardly rectifying channel 4.1 (Kir4.1) in the aqueous humor of diagnosed ...
Elçin Osmanlı, Sabahattin Sül, Ahmet Kaderli, Sema Tamer Kaderli, Ümmühani Türkçü   +4 more
doaj   +1 more source

Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis

Glia, Volume 73, Issue 12, Page 2407-2426, December 2025.
Main Points DEOs are similar to satellite glial cells. DECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. ECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs)
Katja Senf, Sandor Nietzsche, Martin Westermann, Eva M. Neuhaus   +3 more
wiley   +1 more source

Deeper and Deeper on the Role of BK and Kir4.1 Channels in Glioblastoma Invasiveness: A Novel Summative Mechanism?

Frontiers in Neuroscience, 2020
In the last decades, increasing evidence has revealed that a large number of channel protein and ion pumps exhibit impaired expression in cancers. This dysregulation is responsible for high proliferative rates as well as migration and invasiveness ...
Federico Brandalise, Daniela Ratto, Roberta Leone, Federico Olivero, Elisa Roda, Elisa Roda, Carlo Alessandro Locatelli, Maria Grazia Bottone, Paola Rossi   +8 more
doaj   +1 more source

Brain Aquaporin 4 in Hyperammonemia [PDF]

, 2010
In liver failure, congenital enzymopathies of the urea cycle, and other disorders, ammonia may not be properly detoxified and thus hyperammonemia ensues.
Cauli, Omar
core  

Aquaporin water channels in the nervous system. [PDF]

, 2013
The aquaporins (AQPs) are plasma membrane water-transporting proteins. AQP4 is the principal member of this protein family in the CNS, where it is expressed in astrocytes and is involved in water movement, cell migration and neuroexcitation.
A Frigeri, A Kimura, A Marmarou, A Rojek, A Rossi, A Rossi, A Tanghe, A Warth, AJ Wilson, AJ Yool, Alan S. Verkman, AS Filippidis, AS Thrane, AS Verkman, AS Verkman, AS Verkman, B Nico, B Nico, B Wu, B Yang, B Yang, B Yang, BG Nandasena, BJ Jin, BJ Jin, C Geers, C Nicholson, CM Niemietz, CS Furman, D Dolman, DC Lu, DJ Lee, DJ Lee, DK Binder, DK Binder, DK Binder, DK Binder, DM Wingerchuk, DR Johnson, E Ishihara, E Migliati, E Solenov, EA Nagelhus, EA Nagelhus, F Pisani, G Soveral, GM Preston, GP Nicchia, GP Nicchia, GP Nicchia, GT Charras, GT Manley, H Gao, H Ikota, H Wolburg, H Wolburg, H Zhang, H Zhang, H Zhang, I Kleffner, II Arcienega, J Badaut, J Badaut, J Badaut, J Fischbarg, J Hu, J Li, J Li, J Ratelade, J Ruiz-Ederra, JD Ho, JD Neely, JD Neely, JE Rash, JJ Iliff, JL Bennett, JL Venero, JM Carbrey, JM Crane, JM Crane, JM Verbavatz, JS Hub, K Heuser, K Oshio, K Oshio, K Oshio, KI Auguste, L Li, L Tradtrantip, L Tradtrantip, L Tradtrantip, M Amiry-Moghaddam, M Amiry-Moghaddam, M Amiry-Moghaddam, M Eilert-Olsen, M Herrera, M Iwamoto, M Matiello, M Nagahama, M Ozu, M Rabinovitch, Marios C. Papadopoulos, MB Arciszewski, MC Papadopoulos, MC Papadopoulos, MC Papadopoulos, MC Papadopoulos, MC Papadopoulos, MC Sun, MG Mola, MJ Tait, MM Thi, MS Hsu, NH Bass, NN Haj-Yasein, O Bloch, O Bloch, P Hofman, P Padmawar, PW Phuan, R Aharon, RA Fenton, S Jarius, S Nielsen, S Nielsen, S Noell, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Saadoun, S Strohschein, SD Shields, SM Richardson, SR Hinson, T Ma, T Ma, T Tani, T Walz, V Benfenati, VA Lennon, VA Lennon, VA Skucas, VJ Huber, VJ Huber, VM Loitto, W Yang, X Feng, X Yao, X Yu, XN Zeng, Y Cui, Y Fan, Y Fan, Y Hiroaki, Y Yukutake, Z Li, Z Vajda, Z Zador   +161 more
core   +1 more source

LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing

Advanced Science, Volume 12, Issue 41, November 6, 2025.
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang, Yuehui Xi, Qiaojun Fang, Sai Shi, Fei Wang, Fuyu Xian, Zhongyang Zhang, Yuxin Yang, Xishuo Jin, Xiaomin Wang, Chen Cao, Hailin Zhang, Nikita Gamper, Zhigang Xu, Haitao Shen, Ping Lv   +15 more
wiley   +1 more source

ナイジ　カギュウ　ケッカンジョウ　ニ　オケル　ATP　イゾンセイ　ウチムキ　セイリュウ　カリウム　チャネル　KAB-2　Kir4.1　ソノ　トクイテキナ　ブンプ　ト　カギュウナイ　コウデンイ　ノ　セイリツ　トノ　ソウカン [PDF]

Hibino, Hiroshi; Horio, Yoshiyuki; Inanobe, Atsushi; Doi, Katsumi; Ito, Minoru; Yamada, Mitsuhiko; Gotow, Takahiro; Uchiyama, Yasuo; Kawamura, Masaru; Kubo, Takeshi; Kurachi, Yoshihisa. An ATP-Dependent Inwardly Rectifying Potassium Channel, KAB-2(Kir4.1)
ヒビノ, ヒロシ, 日比野, 浩
core   +1 more source

Seizures and disturbed brain potassium dynamics in the leukodystrophy megalencephalic leukoencephalopathy with subcortical cysts [PDF]

, 2018
OBJECTIVE: Loss of function of the astrocyte-specific protein MLC1 leads to the childhood-onset leukodystrophy "megalencephalic leukoencephalopathy with subcortical cysts" (MLC).
Boschert, U, Brouwers, E, Bugiani, M, Dubey, M, Hamilton, EMC, Koch, H, Kole, MHP, Mansvelder, HD, Min, R, Stiedl, O, van der Knaap, MS, Wykes, RC   +11 more
core   +1 more source

Retinal Macroglial Responses in Health and Disease [PDF]

, 2016
Due to their permanent and close proximity to neurons, glial cells perform essential tasks for the normal physiology of the retina. Astrocytes andM¨uller cells (retinal macroglia) provide physical support to neurons and supplement them with several ...
Gallego Collado, Beatriz Isabel, Hoz Montañana, Rosa de, Ramirez Sebastian, Jose Manuel, Ramírez Sebastián, Ana Isabel, Rojas López, María Blanca, Salazar Corral, Juan José, Triviño Casado, Alberto   +6 more
core   +2 more sources

It's All about Timing: The Involvement of Kir4.1 Channel Regulation in Acute Ischemic Stroke Pathology

Frontiers in Cellular Neuroscience, 2018
An acute ischemic stroke is characterized by the presence of a blood clot that limits blood flow to the brain resulting in subsequent neuronal loss.
Meagan Milton, Patrice D. Smith
doaj   +1 more source