Results 131 to 140 of about 7,018 (220)

Astrocytic proteins involved in regulation of the extracellular environment are increased in the Alzheimer's disease middle temporal gyrus

Neurobiology of Disease
Alzheimer's disease (AD) has complex pathophysiology involving numerous cell types and brain processes. Astrocyte involvement in AD is gaining increased attention, however a complete characterisation of astrocytic changes in the AD human brain is ...
Henry Liu, Adelie Y.S. Tan, Nasim F. Mehrabi, Clinton P. Turner, Maurice A. Curtis, Richard L.M. Faull, Mike Dragunow, Malvindar K. Singh-Bains, Amy M. Smith   +8 more
doaj   +1 more source

Müller cell reactivity in response to photoreceptor degeneration in rats with defective polycystin-2.

PLoS ONE, 2014
BackgroundRetinal degeneration in transgenic rats that express a mutant cilia gene polycystin-2 (CMV-PKD2(1/703)HA) is characterized by initial photoreceptor degeneration and glial activation, followed by vasoregression and neuronal degeneration (Feng et
Stefanie Vogler, Thomas Pannicke, Margrit Hollborn, Antje Grosche, Stephanie Busch, Sigrid Hoffmann, Peter Wiedemann, Andreas Reichenbach, Hans-Peter Hammes, Andreas Bringmann   +9 more
doaj   +1 more source

Autism with Seizures and Intellectual Disability: Possible Causative Role of Gain-of-function of the Inwardly-Rectifying K+ Channel Kir4.1

Neurobiology of Disease, 2011
The inwardly-rectifying potassium channel Kir4.1 is a major player in the astrocyte-mediated regulation of [K+]o in the brain, which is essential for normal neuronal activity and synaptic functioning.
Federico Sicca, Paola Imbrici, Maria Cristina D'Adamo, Francesca Moro, Fabrizia Bonatti, Paola Brovedani, Alessandro Grottesi, Renzo Guerrini, Gabriele Masi, Filippo Maria Santorelli, Mauro Pessia   +10 more
doaj   +1 more source

Heterozygous KCNJ10 Variants Affecting Kir4.1 Channel Cause Paroxysmal Kinesigenic Dyskinesia

Movement Disorders
More than 60% of paroxysmal kinesigenic dyskinesia (PKD) cases are of uncertain variants.
Xiaojun Huang, Xin Fu, Jingying Wu, Xin Cheng, Xiaoqi Hong, Ziyi Li, Lan Zheng, Qing Liu, Shendi Chen, Beisha Tang, Yuwu Zhao, Xiaorong Liu, Xunhua Li, Xiaoli Liu, Zaiwei Zhou, Li Wu, Kan Fang, P. Zhong, Mei Zhang, Xinghua Luan, Wotu Tian, Xiaoping Tong, Lihua Cao   +22 more
semanticscholar   +1 more source

Роль астроцитів в підтриманні гомеостазу нервової тканини [PDF]

, 2018
Статтю присвячено огляду даних літератури щодо основних функцій астроцитів, які мають значення для нормального функціонування нервової системи. Йдеться про підтримку вмісту калію в позаклітинній рідині, оскільки астроцити виконують роль буфера для ...
Клопоцький, Г.А., Сілкіна, Ю.В., Хмель, С.І., Худяков, О.Є.   +3 more
core  

ALS-like pathology diminishes swelling of spinal astrocytes in the SOD1 animal model

Frontiers in Cellular Neuroscience
Astrocytes are crucial for the functioning of the nervous system as they maintain the ion homeostasis via volume regulation. Pathological states, such as amyotrophic lateral sclerosis (ALS), affect astrocytes and might even cause a loss of such functions.
Tereza Filipi, Tereza Filipi, Jana Tureckova, Ondrej Vanatko, Ondrej Vanatko, Martina Chmelova, Monika Kubiskova, Monika Kubiskova, Natalia Sirotova, Natalia Sirotova, Stanislava Matejkova, Lydia Vargova, Miroslava Anderova   +12 more
doaj   +1 more source

Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue [PDF]

, 2018
.: The dystrophin glycoprotein complex (DGC) is a multimeric protein assembly associated with either the X-linked cytoskeletal protein dystrophin or its autosomal homologue utrophin. In striated muscle cells, the DGC links the extracellular matrix to the
Fritschy, J., Haenggi, T.
core  

Potassium channel KIR4.1 (KCNJ10) [PDF]

Science-Business eXchange, 2012
openaire   +1 more source

Potassium channel Kir4.1 (KCNJ10) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Albumin and multiple sclerosis [PDF]

, 2016

core   +1 more source