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Altered synaptic homeostasis: a key factor in the pathophysiology of depression. [PDF]
Wang B +10 more
europepmc +1 more source
Designing Neural Dynamics: From Digital Twin Modeling to Regeneration. [PDF]
Tataru CP +6 more
europepmc +1 more source
The Elusive B Cell Antigen in Multiple Sclerosis: Time to Rethink CNS B Cell Functions. [PDF]
Mailaender F +4 more
europepmc +1 more source
Development of perivascular astrocyte processes. [PDF]
Cohen-Salmon M, Guille N, Boulay AC.
europepmc +1 more source
Inwardly Rectifying K+ Channel in Retinal Muller Cells : Comparison with the KAB-2/Kir4.1 Channel Expressed in HEK293T Cells [PDF]
タダ, ヨシヒコ, 多田, 仁彦
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Angiotensin II-Type-1a Receptor and Renal K + Wasting during Overnight Low-Na + Intake.
Duan XP +5 more
europepmc +1 more source
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Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
Nature Chemical BiologyMajor depressive disorder, a prevalent and severe psychiatric condition, necessitates development of new and fast-acting antidepressants. Genetic suppression of astrocytic inwardly rectifying potassium channel 4.1 (Kir4.1) in the lateral habenula ameliorates depression-like phenotypes in mice.
Xiaoyu Zhou +22 more
semanticscholar +3 more sources
Multiple Sclerosis and Antibodies against KIR4.1
New England Journal of Medicine, 2016On protein and peptide assays, there was no significant between-group difference in levels of antibodies against KIR4.1 protein in serum samples obtained from 141 patients with multiple sclerosis and 131 controls.
Probstel, A. K. +6 more
openaire +3 more sources
Neuroscience, 2020
Astrocyte dysfunction, and in particular impaired extracellular potassium spatial buffering, has been postulated to have a potential role in seizure susceptibility and ictogenesis. Inwardly rectifying potassium (Kir) channels, and specifically KIR4.1, have a predominant role in K+ homeostasis and their involvement in neuronal excitability control have ...
Ramona Frida, Moroni +4 more
openaire +2 more sources
Astrocyte dysfunction, and in particular impaired extracellular potassium spatial buffering, has been postulated to have a potential role in seizure susceptibility and ictogenesis. Inwardly rectifying potassium (Kir) channels, and specifically KIR4.1, have a predominant role in K+ homeostasis and their involvement in neuronal excitability control have ...
Ramona Frida, Moroni +4 more
openaire +2 more sources
Astrocytic ion channel Kir4.1 deficit underlies chronic pain.
Sarah Mountadem +2 more
semanticscholar +2 more sources

