Results 201 to 210 of about 7,018 (220)

High-potency block of Kir4.1 channels by pentamidine: Molecular basis

European Journal of Pharmacology, 2017
Inward rectifier potassium (Kir) channels are expressed in almost all mammalian tissues and contribute to a wide range of physiological processes. Kir4.1 channel expression is found in the brain, inner ear, eye, and kidney. Loss-of-function mutations in the pore-forming Kir4.1 subunit cause an autosomal recessive disorder characterized by epilepsy ...
Aréchiga-Figueroa, Iván A, Marmolejo-Murillo, Leticia G, Cui, Meng, Delgado-Ramírez, Mayra, van der Heyden, Marcel A G, Sánchez-Chapula, José A, Rodríguez-Menchaca, Aldo A   +6 more
openaire   +3 more sources

Inhibition of astroglial Kir4.1 channels by selective serotonin reuptake inhibitors

Brain Research, 2007
The inwardly rectifying K+ (Kir) channel Kir4.1 is responsible for astroglial K+ buffering. We recently found that tricyclic antidepressants (TCAs) inhibit Kir4.1 channel currents, which suggests that astroglial Kir currents might be involved in the pharmacological action of antidepressants.
Yukihiro, Ohno, Hiroshi, Hibino, Christoph, Lossin, Atsushi, Inanobe, Yoshihisa, Kurachi   +4 more
openaire   +2 more sources

mTORc2 in the distal convoluted tubule (DCT) stimulates renal K+ excretion by inhibiting basolateral Kir4.1/Kir5.1 and Na-Cl−cotransporter (NCC) during increasing dietary K+ intake

Physiology
Background: The mTORc2 is a multiprotein complex and the core components of mTORc2 contain mTOR (a serine/threonine protein kinase) and RICTOR (rapamycin insensitive companion of mTOR).
Daohong Lin, Wen-Hui Wang, Xin-Peng Duan
semanticscholar   +1 more source

Kir4.1 channel- A universal target in ALS glia

2022
Mitrečić D, Petravić D, editors. Abstracts: International Conference on Neurological Disorders and Neurorestoration; 2022 May 19-22; Dubrovnik, Croatia. Zagreb: Department of Neurology, University Hospital Centre Zagreb: 2022. p. 13. (Neurologia Croatica; Vol. 71; Suppl. 2).
Anđus, Pavle, Perić, Mina, Nikolić, Ljiljana, Bataveljić, Danijela   +3 more
openaire   +1 more source

Unveiling Ketamine's Influence on Astrocytic Kir4.1 Channels Through Multimodal Analysis: Confocal Microscopy, Immunocytochemistry, Fluorescence Analysis, and Electrophysiology.

Methods in molecular biology
Samo Pirnat, Katja Fink, M. Stenovec, M. Kreft, R. Zorec   +4 more
semanticscholar   +1 more source

Intracellular pH regulates the strength of the intrinsic inward rectification of Kir4.1/Kir5.1 channels

Pflügers Archiv: European Journal of Physiology
I. Aréchiga-Figueroa, L. G. Marmolejo-Murillo, Mayra Delgado-Ramírez, Rodrigo Zamora-Cárdenas, Eloy G. Moreno-Galindo, T. Ferrer, R. Navarro-Polanco, J. Sánchez-Chapula, Aldo A. Rodríguez-Menchaca   +8 more
semanticscholar   +1 more source

Astrocytic Kir4.1 channel and O2\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$O_2$$\end{document} account for the tr

Cognitive Neurodynamics
Zhaohui Zhang, Suyu Liu
semanticscholar   +1 more source

TLR9 in satellite glial cells promotes paclitaxel-induced neuropathic pain by reducing Kir4.1 transcription through histone methylation activation

Brain, behavior, and immunity
Qingtian Luo, Jian Jiang, Qing Zhu, Sashuang Wang, Yifei Wu, Nan Li, Xiyuan Ba, Fengling Wu, Xu Liu, Yuhui Luo, Donglin Xiong, Lizu Xiao, Xiang Liao, Zhenhe Huang, Zixian Chen, Changyu Jiang   +15 more
semanticscholar   +1 more source

How Does Kir4.1 turn Touch into Pain?

2021
Makhoul, J, Mountadem, S, Artola, A, Dallel, R, Peirs, Cedric   +4 more
openaire   +1 more source

Kir4.1 channel and voltage-gated calcium channel of astrocyte account for the transition dynamics of seizures.

Journal of Theoretical Biology
Yu Rui, Shu Liu, Suyu Liu
semanticscholar   +1 more source