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INCATools/ontology-access-kit: v0.4.0
, 2023 Major changes some deprecated methods from BasicOntologyInterface have been removed. See: #507 What's Changed re-add translator by @cmungall in https://github.com/INCATools/ontology-access-kit/pull/497 Additional notebooks by @cmungall in https ...
Sierra Moxon +19 more
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Virtual Archaeology Review, 2017 The visualization of 3D reconstructed artifacts often requires significant computing resources. The implementation of an object in a virtual reality (VR) application even necessitates the reduction of the polygonal mesh.
Jesús Muñoz Morcillo +3 more
doaj +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Scientific ReportsWith industrial advancements, the development and use of various additive substances have increased, leading to their potential release into the environment during use and disposal. As a primary tyre additive, the rubber additive, N1-(4-methylpentan-2-yl)
Yooeun Chae +7 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
MatchMates Sprague Rappaport-Type Combination Kit
, 2021 Kit includes a MatchMates aneroid sphygmomanometer and a 31 in. Sprague Rappaport-type stethoscope packed together in a matching nylon carrying case.
core
Connecting local food system actors for climate-friendly public catering in Germany
Journal of Agriculture, Food Systems, and Community DevelopmentClimate-friendly nutrition is a pivotal subject for the future. The Climate-friendly Cafeterias (CliCa) project was initiated as a one-year transformative and transdisciplinary initiative to support the Karlsruhe (Germany) Climate Protection Concept ...
Annika Fricke +4 more
doaj +1 more source
Assessing the effects of a growing electric vehicle fleet using a microscopic travel demand model
European Journal of Transport and Infrastructure Research, 2017 The German government seeks to increase the number of electric vehicles (EV) in the German car fleet to one million by 2020. Since some characteristics of EVs differ from conventional cars, there is an increasing need to assess the various impacts of a ...
Christine Weiss +6 more
doaj +1 more source