Results 71 to 80 of about 2,344,694 (261)
Journal of Research in Education Sciences貧窮不僅是一種經濟現象，同時也影響幼兒的認知、語言與社會情緒發展，並可能導致日後學業成就與社會適應的長期落差。本研究以J. Bruner的「貧窮與童年」理論為基礎，探討貧窮如何影響臺灣經濟弱勢家庭幼兒的發展，透過實證數據分析不同經濟條件下幼兒發展趨勢的差異，進一步探討教育與政策介入的可能性，以提供改善弱勢幼兒發展機會的建議。本研究使用「臺灣幼兒發展調查資料庫」之36月齡組第一至三波追蹤資料進行分析，原始樣本經資料串連處理後，共計納入1,695名幼兒。資料分析先依據不同家庭經濟樣態比例進行加權 ...
許建中 Chien-Chung Hsu +1 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
INCATools/ontology-access-kit: V0.5.11
, 2023 What's Changed minor semsim optimizations by @cmungall in https://github.com/INCATools/ontology-access-kit/pull/582 Use prod api url for monarch_implementation by @kevinschaper in https://github.com/INCATools/ontology-access-kit/pull/591 Add benchmark ...
Sierra Moxon +20 more
core +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
, 2022 In diesem kurzen Video erfährst Du alles, was Du zur virtuellen KIT-Karrieremesse wissen ...
KIT-Career-Service
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
INCATools/ontology-access-kit: v0.5.2
, 2023 What's Changed RustSimImplementation by @hrshdhgd in https://github.com/INCATools/ontology-access-kit/pull/488 Add minimal AmiGOImplementation. Adding biolink source properties by @cmungall in https://github.com/INCATools/ontology-access-kit/pull/538 ...
Sierra Moxon +19 more
core +1 more source
Enhancing neural non-intrusive load monitoring with generative adversarial networks
Energy Informatics, 2018 The application of Deep Learning methodologies to Non-Intrusive Load Monitoring (NILM) gave rise to a new family of Neural NILM approaches which increasingly outperform traditional NILM approaches.
Kaibin Bao +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source