Results 61 to 70 of about 2,344,694 (261)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Non-factorisable contribution to t-channel single-top production

Journal of High Energy Physics, 2022
We compute the non-factorisable O $$ \mathcal{O} $$ ( α s 2 $$ {\alpha}_s^2 $$ ) corrections to t-channel single-top quark production at the LHC. These peculiar corrections arise because of interactions between the heavy- and the light-quark lines and ...
Christian Brønnum-Hansen, Kirill Melnikov, Jérémie Quarroz, Chiara Signorile-Signorile, Chen-Yu Wang   +4 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Diagnostic Performance of Rapid Antigen Tests to Detect Equine Rotavirus A

Viruses
This study describes a comparison of the detection of rotavirus in clinical samples from foals using two commercially available rapid antigen detection (RAD) kits, with the detection of rotavirus nucleic acid via a laboratory-based, in-house, real-time ...
Ann Cullinane, Maura Nelly, Laura Dayot, Gabija Lukaseviciute, Marie Garvey, Jennifer Healy, Robert Gallagher   +6 more
doaj   +1 more source

Design description and validation results for the IFMIF High Flux Test Module as outcome of the EVEDA phase

Nuclear Materials and Energy, 2016
During the Engineering Validation and Engineering Design Activities (EVEDA) phase (2007-2014) of the International Fusion Materials Irradiation Facility (IFMIF), an advanced engineering design of the High Flux Test Module (HFTM) has been developed with ...
F. Arbeiter, A. Abou-Sena, J. Averhals, T. Böttcher, Y. Chen, B. Dolensky, U. Fischer, A. Heinzel, V. Heinzel, T. Heupel, P. Jacquet, Ch. Klein, A. Klix, K. Kondo, J. Konrad, R. Lindau, A. Möslang, A. Muche, H. Piecha, R. Rolli, G. Schlindwein, P. Schubert, F. Schwab, K. Zinn   +23 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Status of Europe’s contribution to the ITER EC system

EPJ Web of Conferences, 2015
The electron cyclotron (EC) system of ITER for the initial configuration is designed to provide 20MW of RF power into the plasma during 3600s and a duty cycle of up to 25% for heating and (co and counter) non-inductive current drive, also used to control
Albajar F., Aiello G., Alberti S., Arnold F., Avramidis K., Bader M., Batista R., Bertizzolo R., Bonicelli T., Braunmueller F., Brescan C., Bruschi A., von Burg B., Camino K., Carannante G., Casarin V., Castillo A., Cauvard F., Cavalieri C., Cavinato M., Chavan R., Chelis J., Cismondi F., Combescure D., Darbos C., Farina D., Fasel D., Figini L., Gagliardi M., Gandini F., Gantenbein G., Gassmann T., Gessner R., Goodman T.P., Gracia V., Grossetti G., Heemskerk C., Henderson M., Hermann V., Hogge J.P., Illy S., Ioannidis Z., Jelonnek J., Jin J., Kasparek W., Koning J., Krause A.S., Landis J.D., Latsas G., Li F., Mazzocchi F., Meier A., Moro A., Nousiainen R., Purohit D., Nowak S., Omori T., van Oosterhout J., Pacheco J., Pagonakis I., Platania P., Poli E., Preis A.K., Ronden D., Rozier Y., Rzesnicki T., Saibene G., Sanchez F., Sartori F., Sauter O., Scherer T., Schlatter C., Schreck S., Serikov A., Siravo U., Sozzi C., Spaeh P., Spichiger A., Strauss D., Takahashi K., Thumm M., Tigelis I., Vaccaro A., Vomvoridis J., Tran M.Q., Weinhorst B.   +85 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source