Results 121 to 130 of about 105,053 (315)

Abatacept Prevents Severe Acute Graft‐Versus‐Host Disease Without Increasing Graft Failure Risk in Pediatric Bone Marrow Failure Syndromes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric patients with inherited or acquired bone marrow failure syndromes (BMFS) often require an allogeneic hematopoietic stem cell transplant (HSCT) to cure the hematological manifestations. Amongst these, those without a matched sibling donor (MSD), are at increased risk for graft failure and are known to tolerate graft‐versus ...
Zahra Hudda, Stella M. Davies, Adam Lane, Deborah E. Schiff, Eric J. Anderson, Parinda A. Mehta, Kasiani C. Myers, Nicholas J. Gloude   +7 more
wiley   +1 more source

Antibacterial activity of eravacycline against Klebsiella pneumoniae isolates: an in vitro study

Microbiology Spectrum
Eravacycline, a novel tetracycline antibiotic, may be an effective treatment option for Klebsiella pneumoniae infections. We thus conducted an in vitro susceptibility analysis for eravacycline in 211 K. pneumoniae isolates.
Yuanzhi Gong, Yuhao Liu, Yunlou Zhu, Shikui Mu, Hanlu Gao, Xin Jing, Yingying Du, Sheng Wang   +7 more
doaj   +1 more source

Nanoparticle‐Based Tetracycline Delivery Systems: Advancing Therapeutic Effectiveness and Tackling Antibiotic Resistance

Particle &Particle Systems Characterization, EarlyView.
This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr, Mehrab Pourmadadi, Fatemeh Yazdian, Hamid Rashedi, Abbas Rahdar, M. Ali Aboudzadeh   +5 more
wiley   +1 more source

Factors influencing mortality in intracranial infections caused by carbapenem-resistant Klebsiella Pneumoniae

Scientific Reports
It remains that intracranial infection has an alarming mortality and morbidity. Klebsiella pneumoniae (KP) have increasingly been isolated in ventriculitis and meningitis episodes.
Chengcheng Lai, Zijun Ma, Yonggang Luo, Yuan Gao, Zhuanghao Wu, Jun Zhang, Weiwei Xu   +6 more
doaj   +1 more source

Newborn with rash due to Klebsiella infection

The Brazilian Journal of Infectious Diseases, 2017
Martínez-Bucio, Víctor, López-Valdés, Julio César   +1 more
openaire   +5 more sources

Severe Skin Necrosis and Crusting Following Disseminated Herpes in a Kidney Transplant Patient: A Rare and Alarming Case

The Kaohsiung Journal of Medical Sciences, EarlyView.
Chung‐Ting Cheng, Lee‐Moay Lim, Hung‐Tien Kuo, Yi‐Wen Chiu   +3 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Epidemiological Investigation of Fluoroquinolone Resistance in Infections Due to Extended‐Spectrum β‐Lactamase–ProducingEscherichia coliandKlebsiella pneumoniae [PDF]

, 2001
Ebbing Lautenbach, Brian L. Strom, Warren B. Bilker, Jean B. Patel, Paul H. Edelstein, Neil O. Fishman   +5 more
openalex   +1 more source

Vancomycin‐Modified DNA Origami Nanostructures for Targeting Bacterial Pathogens

Small Structures, EarlyView.
Applications of DNA origami nanostructures in pathogen detection and antimicrobial drug delivery require their efficient and robust binding to bacterial cells. Here, the cell wall‐binding glycopeptide antibiotic vancomycin is conjugated to selected staple strands and displayed in multivalent arrangements on the DNA origami surface to facilitate the ...
Özge Coşkuner Leineweber, Bhanu K. Pothineni, Nils Schumann, Ulrike Hofmann, Christin Möser, David M. Smith, Guido Grundmeier, Yixin Zhang, Adrian Keller   +8 more
wiley   +1 more source

Outcomes from an intervention study implementing fee‐free culture and susceptibility urine testing in dogs and cats

Veterinary Record, EarlyView.
Abstract Background Urine culture and susceptibility (C&S) testing is important to confirm the presence of infection and aid in antimicrobial selection to ensure that the most appropriate drug is used. Veterinarians often cite the cost of C&S as a prohibitive factor limiting its uptake.
Amy W. Hii, James R. Gilkerson, Kirsten E. Bailey, Ri Scarborough, Anna E. Sri, Magdoline Awad, Lynsey Etheridge, Laura Y. Hardefeldt   +7 more
wiley   +1 more source