Results 11 to 20 of about 105,053 (315)

Bruton’s Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae

Journal of Innate Immunity, 2022
Humans with dysfunctional Bruton’s tyrosine kinase (Btk) are highly susceptible to bacterial infections. Compelling evidence indicates that Btk is essential for B cell-mediated immunity, whereas its role in myeloid cell-mediated immunity against ...
Zhe Liu, Alexander P.N.A. De Porto, Regina De Beer, Joris J.T.H. Roelofs, Onno J. De Boer, Sandrine Florquin, Cornelis Van’t Veer, Rudi W. Hendriks, Tom Van der Poll, Alex F. De Vos   +9 more
doaj   +1 more source

Nosocomial infection and colonization by Klebsiella trevisanii [PDF]

Journal of Clinical Microbiology, 1986
During an 18-month period we identified two cases of septicemia and 24 examples of colonization of humans by Klebsiella trevisanii. Organisms were identified using the API 20EC and API 147 assimilation galleries. Of 147 clinical isolates initially identified as K. oxytoca, 18% were found to be K. trevisanii. Tracheal aspirate was the most common source
J. Freney, D. Izard, S Madier, J. Fleurette, H. Alexandre, H. Leclerc, Françoise Gavini   +6 more
openaire   +3 more sources

Purple urine bag syndrome in end-stage chronic kidney disease

Brazilian Journal of Nephrology, 2014
Introduction: When faced with violet, purple or purplish-blue urine, clinicians should consider urinary tract infection in their differential diagnosis.
Guillermo Delgado, Michel Martínez-Reséndez, Adrián Camacho-Ortiz   +2 more
doaj   +1 more source

Klebsiella species: Taxonomy, hypervirulence and multidrug resistance

EBioMedicine, 2022
Summary: Members of the genus Klebsiella have rapidly evolved within the past decade, generating organisms that simultaneously exhibit both multidrug resistance and hypervirulence (MDR-hv) phenotypes; such organisms are associated with severe hospital ...
Ning Dong, Xuemei Yang, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen   +4 more
doaj   +1 more source

In vitro activity of novel apramycin-dextran nanoparticles and free apramycin against selected Dutch and Pakistani Klebsiella pneumonia isolates

Heliyon, 2023
Klebsiella pneumoniae are bacteria associated with respiratory tract infections and are increasingly becoming resistant to antibiotics, including carbapenems.
Nagina Atlas, Bushra Uzair, Julie Movellan, Raquel Gracia, Damien Dupin, Iraida Loinaz, Cornelus F. van Nostrum, John P. Hays   +7 more
doaj   +1 more source

Cure of recurring Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae septic shock episodes due to complicated soft tissue infection using a ceftazidime and avibactam-based regimen: a case report

Journal of Medical Case Reports, 2019
Background Infections caused by multidrug-resistant Enterobacteriaceae are hard to treat and life-threatening due to reduced therapeutic options. Systemic infections caused by Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae strains ...
Giustino Parruti, Antonella Frattari, Ennio Polilli, Vincenzo Savini, Antonina Sciacca, Augusta Consorte, Donatella Concetta Cibelli, Adriana Agostinone, Francesco Di Masi, Alessandro Pieri, Pierluigi Cacciatore, Giancarlo Di Iorio, Paolo Fazii, Tullio Spina   +13 more
doaj   +1 more source

Management of KPC-producing Klebsiella pneumoniae infections [PDF]

Clinical Microbiology and Infection, 2018
Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) has become one of the most important contemporary pathogens, especially in endemic areas.To provide practical suggestion for physicians dealing with the management of KPC-KP infections in critically ill patients, based on expert opinions.PubMed search for relevant publications ...
Bassetti, M.; Giacobbe, D. R.; Giamarellou, H.; Viscoli, C.; Daikos, G. L.; Dimopoulos, G.; De Rosa, F. G.; Giamarellos-Bourboulis, E. J.; Rossolini, G. M.; Righi, E.; Karaiskos, I.; Tumbarello, M.; Nicolau, D. P.; Viale, P. L.; Poulakou, G.   +15 more
openaire   +8 more sources

SIDEROPHORE RECEPTOR PROTEIN FROM KLEBSIELLA PNEUMONIAE AS A PROMISING IMMUNOGEN FOR SEROTYPE-INDEPENDENT THERAPEUTIC LEAD DEVELOPMENT

International Journal of Infectious Diseases, 2023
Intro: Klebsiella pneumoniae causes wide range of infections including urinary tract infections, sepsis, bacteremia, pneumonia and liver abscesses. The emergence of multi drug resistance in this bacterium led to a major setback for clinical management ...
S. Pandey, S. Dhyani, P. Joshi, D. Kumar, A. Chauhan, S. Awasthi, M. Yadav, S. Gupta, S. Tanwar, R. Dwivedi, C. Singhal, N. Kumar, S. Chaudhuri   +12 more
doaj   +1 more source

A hospital-based matched case–control study to identify clinical outcome and risk factors associated with carbapenem-resistant Klebsiella pneumoniae infection

BMC Infectious Diseases, 2013
Background Healthcare-associated infections caused by Klebsiella pneumoniae isolates are increasing and few effective antibiotics are currently available to treat patients. We observed decreased carbapenem susceptibility among K. pneumoniae isolated from
Correa Luci, Martino Marines Dalla Valle, Siqueira Itacy, Pasternak Jacyr, Gales Ana Cristina, Silva Claudia Vallone, Camargo Thiago Zinsly Sampaio, Scherer Patricia Faria, Marra Alexandre Rodrigues   +8 more
doaj   +1 more source

Risk Factors for Carbapenem-resistant Klebsiella pneumoniae Infection and Mortality of Klebsiella pneumoniae Infection

Chinese Medical Journal, 2018
Klebsiella pneumoniae (KP) is a pathogen commonly causing nosocomial infection. Carbapenem-resistant KP (CRKP) is more resistant to multiple antimicrobial drugs than carbapenem-susceptible KP (CSKP) isolates. The aim of the present study was to identify the risk factors for CRKP infection and the predictors of mortality among KP-infected adult patients.
Li-Ying Sun, Lei Huang, Zhe Wang, Ran-Ran Qin   +3 more
openaire   +4 more sources