Results 41 to 50 of about 111,664 (261)

Factors Associated with Extended-Spectrum β-Lactamases and Carbapenem-Resistant Klebsiella pneumoniae Bloodstream Infections: A Five-Year Retrospective Study

Pathogens, 2023
Klebsiella pneumoniae is one of the leading causes of nosocomial infections. It has been estimated that nosocomial infection by Klebsiella pneumoniae comprises 3–8% of all nosocomial infections.
Andreas G. Tofarides, Panagiotis Dimitriou, Georgios K. Nikolopoulos, Dimitrios Rogkas, Christina Flourou, Elina Khattab, Diamanto Kasapi, Chara Azina, Eirini Christaki   +8 more
doaj   +1 more source

Bilateral SERS‐Microneedle Patch for Co‐Diagnosis of Diabetes Mellitus and Tuberculosis Comorbidity

Advanced Science, EarlyView.
Our study introduced a U@mP@Au‐mediated bilateral SERS‐microneedle patch for analyzing glucose levels from ISF and sensitively detecting TB biomarkers from sputum, respectively. This integrated dual‐analyte detecting platform can be used for co‐diagnosis of diabetes mellitus (DM) and tuberculosis (TB) comorbidity, which was demonstrated in ex vivo ...
Xueqin Huang, Lingzhi Chen, Jing Xu, Jiaqi Yu, Shanze Chen, Huaihong Cai, Yanguang Cong, Pinghua Sun, Jiang Pi, Lang Rao, Jierong Chen, Junxia Zheng, Haibo Zhou   +12 more
wiley   +1 more source

Impact of Prophylactic Cefepime on Surgical Site Infection and Severe Morbidity in Patients Who Underwent Pancreaticoduodenectomy With Preoperative Biliary Drainage

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Although prophylactic broad‐spectrum antibiotics can reduce postoperative complications after pancreaticoduodenectomy (PD), the optimal regimen remains uncertain. This study evaluated the impact of prophylactic cefepime (CFPM) on surgical site infection (SSI) and severe morbidity after PD with preoperative biliary drainage.
Genki Watanabe, Akihiro Murata, Yu Kasamatsu, Atsushi Ishihara, Daisuke Nagashima, Tetsuzo Tashima, Shintaro Kodai, Akishige Kanazawa, Sadatoshi Shimizu   +8 more
wiley   +1 more source

Study of Klebsiella pneumoniae Vaccine Based on the Epitopes of Outer Membrane Proteins: An Immunoinformatic Approach [PDF]

Journal of Ardabil University of Medical Sciences
Background: Klebsiella pneumoniae (K. pneumoniae) infections are usually considered life-threatening. Vaccination plays a crucial role in reducing the spread and mortality of infectious diseases.
Hamid Vaez, Mohammad Amin Sargazi, Ali Zeidabadi, Mohammadreza Javan, Farzad Khademi, Abbas Pishdadian   +5 more
doaj  

Physiochemical characterization of a potential Klebsiella phage MKP-1 and analysis of its application in reducing biofilm formation

Frontiers in Microbiology
The common intestinal pathogen Klebsiella pneumoniae (K. pneumoniae) is one of the leading causes of fatal superbug infections that can resist the effects of commonly prescribed medicines.
Sayani Das, Sandip Kaledhonkar
doaj   +1 more source

Epidemiological characteristics and molecular evolution mechanisms of carbapenem-resistant hypervirulent Klebsiella pneumoniae

Frontiers in Microbiology, 2022
Carbapenem-resistant hypervirulent Klebsiella pneumoniae (CR-hvKP), a type of Klebsiella pneumoniae (KP) that exhibits hypervirulence and carbapenem resistance phenotypes, can cause severe infections, both hospital- and community-acquired infections.
Yu-Ling Han, Yu-Ling Han, Xu-Hui Wen, Xu-Hui Wen, Wen Zhao, Xi-Shan Cao, Jian-Xun Wen, Jun-Rui Wang, Zhi-De Hu, Wen-Qi Zheng, Wen-Qi Zheng   +10 more
doaj   +1 more source

Effect of Broad‐Spectrum Antibiotic Prophylaxis on Post‐Pancreatoduodenectomy Infectious Complications: Nationwide Inpatient Database Study in Japan

Annals of Gastroenterological Surgery, EarlyView.
Using a nationwide Japanese inpatient database, we evaluated whether broad‐spectrum antibiotic prophylaxis improves postoperative outcomes after pancreatoduodenectomy compared with narrow‐spectrum antibiotics. In propensity score–weighted analyses of 45 099 patients, broad‐spectrum prophylaxis was associated with significantly lower rates of intra ...
Hiroki Kitagawa, Shotaro Aso, Yuki Hirano, Kenichiro Uemura, Keita Kouzu, Satoru Matsuda, Hiroki Matsui, Kiyohide Fushimi, Junichi Sasaki, Yuko Kitagawa, Hideo Yasunaga   +10 more
wiley   +1 more source

Bacteriophages with depolymerase activity in the control of antibiotic resistant Klebsiella pneumoniae biofilms

Scientific Reports, 2023
Klebsiella pneumoniae is associated with a variety of infections, such as pneumonia, urogenital infection, liver abscess, and bloodstream infection. It is especially dangerous for patients in medical facilities, where it can cause ventilator-associated ...
Fedor Zurabov, Egor Glazunov, Tatiana Kochetova, Viktoria Uskevich, Valentina Popova   +4 more
doaj   +1 more source

Modelling the Gastrointestinal Carriage of Klebsiella pneumoniae Infections

mBio, 2022
Klebsiella pneumoniae is one of the pathogens that is sweeping the world in the antibiotic resistance pandemic. Klebsiella colonizes the nasopharynx and the gut of healthy subjects in an asymptomatic manner, making gut colonization a requisite for infection.
Ricardo Calderon-Gonzalez, Alix Lee, Guillermo Lopez-Campos, Steven J. Hancock, Joana Sa-Pessoa, Amy Dumigan, Ronan McMullan, Eric L. Campbell, Jose A. Bengoechea   +8 more
openaire   +7 more sources

Interspecies Biofilm Dynamics Among Staphylococci: Inflammatory Contributions to Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Introduction Staphylococcus species are frequently isolated from the sinonasal niche of chronic rhinosinusitis (CRS) patients. While Staphylococcus aureus is often associated with recalcitrant CRS, Staphylococcus epidermidis and Staphylococcus lugdunensis are largely deemed commensal.
Sintayehu Ambachew, Mahnaz Ramezanpour, Clare M. Cooksley, Sholeh Feizi, Muhammed Awad, Kevin Aaron Fenix, Peter‐John Wormald, Alkis J. Psaltis, Sarah Vreugde   +8 more
wiley   +1 more source