Results 51 to 60 of about 3,819,128 (202)

High prevalence of antimicrobial resistance genes in multidrug-resistant-ESBLs-producing Klebsiella pneumoniae post-COVID-19 pandemic

Iranian Journal of Microbiology
Background and Objectives: Klebsiella pneumoniae is a common pathogen associated with healthcare-related infections. It is particularly notable for its ability to develop resistance to multiple antibiotics, making treatment challenging. During the COVID-
Golnar Rahimzadeh, Shaghayegh Rezai, Ghazal Abbasi, Saman Soleimanpour, Reza Valadan, Laleh Vahedi, Somayeh Sheidaei, Faezeh Sadat Movahedi, Raha Rezai, Mohammad Sadegh Rezai   +9 more
doaj   +1 more source

Microbiological and Clinical Characteristics of Hypermucoviscous Klebsiella pneumoniae Isolates Associated with Invasive Infections in China

Frontiers in Cellular and Infection Microbiology, 2017
A distinctive syndrome caused by hypermucoviscous Klebsiella pneumoniae (HMKP) including pyogenic liver abscess (PLA) is now becoming a globally emerging disease. In the present study, 22.8% (84/369) of K.
Yinjuan Guo, Shanshan Wang, L. Zhan, Ye Jin, Jingjing Duan, Zhihao Hao, Jingnan Lv, Xiuqin Qi, Liang Chen, B. Kreiswirth, Liangxing Wang, F. Yu   +11 more
semanticscholar   +1 more source

Add-On Therapy with Ertapenem in Infections with Multidrug Resistant Gram-Negative Bacteria: Pediatric Experience

Case Reports in Infectious Diseases, 2017
Optimal therapy for infections with carbapenem resistant GNB is not well established due to the weakness of data. Patients presenting with bloodstream infections caused by multidrug resistant Klebsiella pneumoniae were treated with a combination ...
Sevgen Tanır Basaranoglu, Yasemin Ozsurekci, Kubra Aykac, Kamile Oktay Arıkan, Ayse Buyukcam, Ali Bulent Cengiz, Mehmet Ceyhan, Ates Kara   +7 more
doaj   +1 more source

Klebsiella pneumoniae Reduces SUMOylation To Limit Host Defense Responses

mBio, 2020
Klebsiella pneumoniae is an important cause of multidrug-resistant infections worldwide. Understanding the virulence mechanisms of K. pneumoniae is a priority and timely to design new therapeutics. Here, we demonstrate that K.
Joana Sá-Pessoa, Kornelia Przybyszewska, Filipe Nuno Vasconcelos, Amy Dumigan, Christian G. Frank, Laura Hobley, Jose A. Bengoechea   +6 more
doaj   +1 more source

Carbapenem-resistant Klebsiella pneumoniae capsular types, antibiotic resistance and virulence factors in China: a longitudinal, multi-centre study

Nature Microbiology
Epidemiological knowledge of circulating carbapenem-resistant Klebsiella pneumoniae (CRKP) is needed to develop effective strategies against this public health threat. Here we present a longitudinal analysis of 1,017 CRKP isolates recovered from patients
F. Hu, Yuqing Pan, Heng Li, Renru Han, Xiao Liu, Ruijing Ma, Yongqin Wu, Heyuan Lun, Xiaohua Qin, Jiayin Li, Aixi Wang, Min Zhou, Bing Liu, Zhemin Zhou, Ping He   +14 more
semanticscholar   +1 more source

In-hospital Medical Costs of Infections Caused by Carbapenem-resistant Klebsiella pneumoniae.

Clinical Infectious Diseases, 2018
Background Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a major health threat, but the economic impact of carbapenem resistance in K. pneumoniae infections remains largely uninvestigated.
Wenzhi Huang, F. Qiao, Yinying Zhang, Jing Huang, Yuhua Deng, Jinwen Li, Z. Zong   +6 more
semanticscholar   +1 more source

Development of a broad spectrum glycoconjugate vaccine to prevent wound and disseminated infections with Klebsiella pneumoniae and Pseudomonas aeruginosa

PLoS ONE, 2018
Klebsiella pneumoniae (KP) and Pseudomonas aeruginosa (PA) are important human pathogens that are associated with a range of infection types, including wound and disseminated infections.
N. Hégerlé, Myeongjin Choi, J. Sinclair, M. Amin, Morgane Ollivault-Shiflett, B. Curtis, Rachel S Laufer, S. Shridhar, Jerod Brammer, F. Toapanta, I. A. Holder, M. Pasetti, A. Lees, S. Tennant, A. Cross, R. Simon   +15 more
semanticscholar   +1 more source

Successful treatment of lower urinary tract infections with oral fosfomycin: a report of three cases

Revista da Sociedade Brasileira de Medicina Tropical, 2015
Infections due to multidrug-resistant organisms continue to increase, and therapeutic options remain scarce. Given this challenge, it has become necessary to use older antimicrobials for treatment of these pathogens.
Juliana Oliveira da Silva, Maria Cecilia Zorat Yu, André Doi, Maria Rita Elmor de Araujo, Pedro Aurélio Mathiasi Neto, Guilherme Henrique Campos Furtado   +5 more
doaj   +1 more source

Antibiotic Resistance Pattern and the Prevalence of Extended Spectrum Beta-Lactamases (ESBLs) in Urinary Isolates of Klebsiella Pneumoniae

Medical Laboratory Journal, 2015
Background and Objective: Klebsiella pneumoniae is an opportunistic nosocomial pathogen causing a variety of infections including urinary tract infections, pneumonia, septicemia, wound infections and infections in the intensive care units. Since the ESBL
Shahraki, SH, Bokaeian, M, Rigi, SH
doaj  

Reduced Incidence of Carbapenem-Resistant Klebsiella pneumoniae Infections in Cardiac Surgery Patients after Implementation of an Antimicrobial Stewardship Project

Antibiotics, 2019
Infections due to carbapenem-resistant Klebsiella pneumoniae (CR-Kp) are associated with increased mortality in cardiac surgery patients. In this short communication, we report on the changes in the incidence of CR-Kp colonization and CR-Kp infection in ...
Daniele Roberto Giacobbe, Antonio Salsano, Filippo Del Puente, Francesco Campanini, Giovanni Mariscalco, Anna Marchese, Claudio Viscoli, Francesco Santini   +7 more
doaj   +1 more source