Results 21 to 30 of about 111,664 (261)

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

SIDEROPHORE RECEPTOR PROTEIN FROM KLEBSIELLA PNEUMONIAE AS A PROMISING IMMUNOGEN FOR SEROTYPE-INDEPENDENT THERAPEUTIC LEAD DEVELOPMENT

International Journal of Infectious Diseases, 2023
Intro: Klebsiella pneumoniae causes wide range of infections including urinary tract infections, sepsis, bacteremia, pneumonia and liver abscesses. The emergence of multi drug resistance in this bacterium led to a major setback for clinical management ...
S. Pandey, S. Dhyani, P. Joshi, D. Kumar, A. Chauhan, S. Awasthi, M. Yadav, S. Gupta, S. Tanwar, R. Dwivedi, C. Singhal, N. Kumar, S. Chaudhuri   +12 more
doaj   +1 more source

Shiga Toxin-Producing E. coli (STEC) from Danish Patients, 1997–2023: Diagnostic Trends and Bacteriological Findings

Microorganisms
Implementation of molecular detection methodology of Shiga toxin-producing Escherichia coli (STEC) in Danish patients began in 1997. Since then, changes in molecular detection methods and diagnostic criteria have led to the present situation, in which ...
Flemming Scheutz, Katrine Grimstrup Joensen, Susanne Schjørring, Bente Olesen, Jørgen Engberg, Hanne Marie Holt, Hans Linde Nielsen, Lars Lemming, Michael Pedersen, Lisbeth Lützen, Marc Trunjer Kusk Nielsen, Kristian Schønning, Eva Møller Nielsen   +12 more
doaj   +1 more source

Frequency and Antibiotic Susceptibility Pattern of Klebsiella Species in Blood Culture of Paediatric Population [PDF]

Journal of Sharif Medical & Dental College, 2023
Objective: To isolate Klebsiella species in the blood culture of pediatric patients, evaluate its antimicrobial susceptibility, and determine the frequency of extended spectrum beta-lactamase (ESBL) among Klebsiella species.
Nazia Akber Mir, Nadeem Younas, Attia Lateef, Babar Yasin, Hina Ashraf, Kiran Fatima, Ayesha Javed, Awais Altaf, Syed Zeeshan Haider   +8 more
doaj  

Crippling of Klebsiella pneumoniae virulence by metformin, N-acetylcysteine and secnidazole

BMC Microbiology, 2023
Introduction The emergence of multidrug-resistant Klebsiella pneumoniae in hospitals represents a serious threat to public health. Infections caused by Klebsiella pneumoniae are widespread in healthcare institutions, mainly pneumonia, bloodstream ...
Shokri M. Shafik, Hisham A. Abbas, Nehal Yousef, Moustafa M. Saleh   +3 more
doaj   +1 more source

Phenotypic Characterization of Virulence Factors and Antibiogram of Klebsiella pneumoniae Isolates from Various Clinical Samples – A Cross Sectional Study

Journal of Pure and Applied Microbiology, 2022
K. pneumoniae is known to cause hospital and community acquired infections. It is usually associated with upper & lower respiratory infections, septicaemia, urinary tract infection, wound infections, neonatal sepsis, meningitis, and endophthalmitis.
Madhavi S. Hullur, Arvind Natarajan, P.N. Sreeramulu   +2 more
doaj   +1 more source

Ceftriaxone- and ceftazidime-resistant species, , and methicillin-resistant dominate caesarean surgical site infections at Mulago Hospital, Kampala, Uganda

SAGE Open Medicine, 2020
Objectives: The aim of this study was to determine the proportion and mechanism of resistance to ceftriaxone and ceftazidime among Klebsiella species and Escherichia coli and examine the burden of methicillin-resistant Staphylococcus aureus from ...
Yvonne N Wekesa, Fatuma Namusoke, Musa Sekikubo, Dennis Wandera Mango, Freddie Bwanga   +4 more
doaj   +1 more source

Risk Factors for Carbapenem-resistant Klebsiella pneumoniae Infection and Mortality of Klebsiella pneumoniae Infection

Chinese Medical Journal, 2018
Klebsiella pneumoniae (KP) is a pathogen commonly causing nosocomial infection. Carbapenem-resistant KP (CRKP) is more resistant to multiple antimicrobial drugs than carbapenem-susceptible KP (CSKP) isolates. The aim of the present study was to identify the risk factors for CRKP infection and the predictors of mortality among KP-infected adult patients.
Zhe Wang, Ran-Ran Qin, Lei Huang, Li-Ying Sun   +3 more
openaire   +3 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Carbapenem-resistant Klebsiella pneumoniae colonization in pediatric and neonatal intensive care units: risk factors for progression to infection

Brazilian Journal of Infectious Diseases, 2016
Background: Little is known about factors associated with carbapenem-resistant Klebsiella pneumoniae infections in pediatric patients, who are initally colonized with carbapenem-resistant Klebsiella pneumoniae. Materials and methods: A retrospective case–
Hacer Akturk, Murat Sutcu, Ayper Somer, Derya Aydın, Rukiye Cihan, Aslı Ozdemir, Asuman Coban, Zeynep Ince, Agop Citak, Nuran Salman   +9 more
doaj   +1 more source