Results 21 to 30 of about 112,576 (260)

Cure of recurring Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae septic shock episodes due to complicated soft tissue infection using a ceftazidime and avibactam-based regimen: a case report

Journal of Medical Case Reports, 2019
Background Infections caused by multidrug-resistant Enterobacteriaceae are hard to treat and life-threatening due to reduced therapeutic options. Systemic infections caused by Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae strains ...
Giustino Parruti, Antonella Frattari, Ennio Polilli, Vincenzo Savini, Antonina Sciacca, Augusta Consorte, Donatella Concetta Cibelli, Adriana Agostinone, Francesco Di Masi, Alessandro Pieri, Pierluigi Cacciatore, Giancarlo Di Iorio, Paolo Fazii, Tullio Spina   +13 more
doaj   +1 more source

Frequency and Antibiotic Susceptibility Pattern of Klebsiella Species in Blood Culture of Paediatric Population [PDF]

Journal of Sharif Medical & Dental College, 2023
Objective: To isolate Klebsiella species in the blood culture of pediatric patients, evaluate its antimicrobial susceptibility, and determine the frequency of extended spectrum beta-lactamase (ESBL) among Klebsiella species.
Nazia Akber Mir, Nadeem Younas, Attia Lateef, Babar Yasin, Hina Ashraf, Kiran Fatima, Ayesha Javed, Awais Altaf, Syed Zeeshan Haider   +8 more
doaj  

SIDEROPHORE RECEPTOR PROTEIN FROM KLEBSIELLA PNEUMONIAE AS A PROMISING IMMUNOGEN FOR SEROTYPE-INDEPENDENT THERAPEUTIC LEAD DEVELOPMENT

International Journal of Infectious Diseases, 2023
Intro: Klebsiella pneumoniae causes wide range of infections including urinary tract infections, sepsis, bacteremia, pneumonia and liver abscesses. The emergence of multi drug resistance in this bacterium led to a major setback for clinical management ...
S. Pandey, S. Dhyani, P. Joshi, D. Kumar, A. Chauhan, S. Awasthi, M. Yadav, S. Gupta, S. Tanwar, R. Dwivedi, C. Singhal, N. Kumar, S. Chaudhuri   +12 more
doaj   +1 more source

Shiga Toxin-Producing E. coli (STEC) from Danish Patients, 1997–2023: Diagnostic Trends and Bacteriological Findings

Microorganisms
Implementation of molecular detection methodology of Shiga toxin-producing Escherichia coli (STEC) in Danish patients began in 1997. Since then, changes in molecular detection methods and diagnostic criteria have led to the present situation, in which ...
Flemming Scheutz, Katrine Grimstrup Joensen, Susanne Schjørring, Bente Olesen, Jørgen Engberg, Hanne Marie Holt, Hans Linde Nielsen, Lars Lemming, Michael Pedersen, Lisbeth Lützen, Marc Trunjer Kusk Nielsen, Kristian Schønning, Eva Møller Nielsen   +12 more
doaj   +1 more source

Crippling of Klebsiella pneumoniae virulence by metformin, N-acetylcysteine and secnidazole

BMC Microbiology, 2023
Introduction The emergence of multidrug-resistant Klebsiella pneumoniae in hospitals represents a serious threat to public health. Infections caused by Klebsiella pneumoniae are widespread in healthcare institutions, mainly pneumonia, bloodstream ...
Shokri M. Shafik, Hisham A. Abbas, Nehal Yousef, Moustafa M. Saleh   +3 more
doaj   +1 more source

Phenotypic Characterization of Virulence Factors and Antibiogram of Klebsiella pneumoniae Isolates from Various Clinical Samples – A Cross Sectional Study

Journal of Pure and Applied Microbiology, 2022
K. pneumoniae is known to cause hospital and community acquired infections. It is usually associated with upper & lower respiratory infections, septicaemia, urinary tract infection, wound infections, neonatal sepsis, meningitis, and endophthalmitis.
Madhavi S. Hullur, Arvind Natarajan, P.N. Sreeramulu   +2 more
doaj   +1 more source

Chemoenzymatic Radiosynthesis of a Gluconate Transporter‐Targeted In Vivo Bacterial Sensor From Clinical [18F]FDG

Angewandte Chemie, EarlyView.
An efficient radiosynthesis of fluorine‐18 labeled gluconic acid ([18F]FGA) was developed using two readily available materials, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose ([18F]FDG) and glucose oxidase. [18F]FGA is highly specific for bacterial gluconate metabolism mediated by gluconate permease (GntP) and gluconate kinase (GntK), with rapid clearance, low off ...
Sang Hee Lee, Jung Min Kim, Joseph Blecha, Robert R. Flavell, Michael A. Ohliger, Joanne Engel, Youngho Seo, David M. Wilson   +7 more
wiley   +2 more sources

Risk Factors for Carbapenem-resistant Klebsiella pneumoniae Infection and Mortality of Klebsiella pneumoniae Infection

Chinese Medical Journal, 2018
Klebsiella pneumoniae (KP) is a pathogen commonly causing nosocomial infection. Carbapenem-resistant KP (CRKP) is more resistant to multiple antimicrobial drugs than carbapenem-susceptible KP (CSKP) isolates. The aim of the present study was to identify the risk factors for CRKP infection and the predictors of mortality among KP-infected adult patients.
Zhe Wang, Ran-Ran Qin, Lei Huang, Li-Ying Sun   +3 more
openaire   +3 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Ceftriaxone- and ceftazidime-resistant species, , and methicillin-resistant dominate caesarean surgical site infections at Mulago Hospital, Kampala, Uganda

SAGE Open Medicine, 2020
Objectives: The aim of this study was to determine the proportion and mechanism of resistance to ceftriaxone and ceftazidime among Klebsiella species and Escherichia coli and examine the burden of methicillin-resistant Staphylococcus aureus from ...
Yvonne N Wekesa, Fatuma Namusoke, Musa Sekikubo, Dennis Wandera Mango, Freddie Bwanga   +4 more
doaj   +1 more source