Results 11 to 20 of about 109,518 (258)

Bruton’s Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae

Journal of Innate Immunity, 2022
Humans with dysfunctional Bruton’s tyrosine kinase (Btk) are highly susceptible to bacterial infections. Compelling evidence indicates that Btk is essential for B cell-mediated immunity, whereas its role in myeloid cell-mediated immunity against ...
Zhe Liu, Alexander P.N.A. De Porto, Regina De Beer, Joris J.T.H. Roelofs, Onno J. De Boer, Sandrine Florquin, Cornelis Van’t Veer, Rudi W. Hendriks, Tom Van der Poll, Alex F. De Vos   +9 more
doaj   +1 more source

Purple urine bag syndrome in end-stage chronic kidney disease

Brazilian Journal of Nephrology, 2014
Introduction: When faced with violet, purple or purplish-blue urine, clinicians should consider urinary tract infection in their differential diagnosis.
Guillermo Delgado, Michel Martínez-Reséndez, Adrián Camacho-Ortiz   +2 more
doaj   +1 more source

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

Hepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole, Kristin Kaasen Jørgensen, Kristian Holm, Peder R. Braadland, Malin Holm Meyer‐Myklestad, Asle Wilhelm Medhus, Dag Henrik Reikvam, Alexandra Götz, Krzysztof Grzyb, Kirsten Muri Boberg, Tom Hemming Karlsen, Martin Kummen, Johannes R. Hov   +12 more
wiley   +1 more source

Klebsiella bacteraemia: community versus nosocomial infection [PDF]

QJM, 1996
In the period 1988-1993, 241 patients had Klebsiella bacteraemia at our medical centre. The annual number of patients with positive blood cultures increased from 306 in 1988 to 622 in 1993, representing a 4.5-6% positivity rate of drawn cultures. After E. coli, Klebsiella was the leading cause of Gram-negative bacteraemia.
A M, Yinnon, A, Butnaru, D, Raveh, Z, Jerassy, B, Rudensky   +4 more
openaire   +2 more sources

Klebsiella species: Taxonomy, hypervirulence and multidrug resistance

EBioMedicine, 2022
Summary: Members of the genus Klebsiella have rapidly evolved within the past decade, generating organisms that simultaneously exhibit both multidrug resistance and hypervirulence (MDR-hv) phenotypes; such organisms are associated with severe hospital ...
Ning Dong, Xuemei Yang, Edward Wai-Chi Chan, Rong Zhang, Sheng Chen   +4 more
doaj   +1 more source

A hospital-based matched case–control study to identify clinical outcome and risk factors associated with carbapenem-resistant Klebsiella pneumoniae infection

BMC Infectious Diseases, 2013
Background Healthcare-associated infections caused by Klebsiella pneumoniae isolates are increasing and few effective antibiotics are currently available to treat patients. We observed decreased carbapenem susceptibility among K. pneumoniae isolated from
Correa Luci, Martino Marines Dalla Valle, Siqueira Itacy, Pasternak Jacyr, Gales Ana Cristina, Silva Claudia Vallone, Camargo Thiago Zinsly Sampaio, Scherer Patricia Faria, Marra Alexandre Rodrigues   +8 more
doaj   +1 more source

In vitro activity of novel apramycin-dextran nanoparticles and free apramycin against selected Dutch and Pakistani Klebsiella pneumonia isolates

Heliyon, 2023
Klebsiella pneumoniae are bacteria associated with respiratory tract infections and are increasingly becoming resistant to antibiotics, including carbapenems.
Nagina Atlas, Bushra Uzair, Julie Movellan, Raquel Gracia, Damien Dupin, Iraida Loinaz, Cornelus F. van Nostrum, John P. Hays   +7 more
doaj   +1 more source

Cure of recurring Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae septic shock episodes due to complicated soft tissue infection using a ceftazidime and avibactam-based regimen: a case report

Journal of Medical Case Reports, 2019
Background Infections caused by multidrug-resistant Enterobacteriaceae are hard to treat and life-threatening due to reduced therapeutic options. Systemic infections caused by Klebsiella pneumoniae carbapenemase-producing Klebsiella pneumoniae strains ...
Giustino Parruti, Antonella Frattari, Ennio Polilli, Vincenzo Savini, Antonina Sciacca, Augusta Consorte, Donatella Concetta Cibelli, Adriana Agostinone, Francesco Di Masi, Alessandro Pieri, Pierluigi Cacciatore, Giancarlo Di Iorio, Paolo Fazii, Tullio Spina   +13 more
doaj   +1 more source

SIDEROPHORE RECEPTOR PROTEIN FROM KLEBSIELLA PNEUMONIAE AS A PROMISING IMMUNOGEN FOR SEROTYPE-INDEPENDENT THERAPEUTIC LEAD DEVELOPMENT

International Journal of Infectious Diseases, 2023
Intro: Klebsiella pneumoniae causes wide range of infections including urinary tract infections, sepsis, bacteremia, pneumonia and liver abscesses. The emergence of multi drug resistance in this bacterium led to a major setback for clinical management ...
S. Pandey, S. Dhyani, P. Joshi, D. Kumar, A. Chauhan, S. Awasthi, M. Yadav, S. Gupta, S. Tanwar, R. Dwivedi, C. Singhal, N. Kumar, S. Chaudhuri   +12 more
doaj   +1 more source

Frequency and Antibiotic Susceptibility Pattern of Klebsiella Species in Blood Culture of Paediatric Population [PDF]

Journal of Sharif Medical & Dental College, 2023
Objective: To isolate Klebsiella species in the blood culture of pediatric patients, evaluate its antimicrobial susceptibility, and determine the frequency of extended spectrum beta-lactamase (ESBL) among Klebsiella species.
Nazia Akber Mir, Nadeem Younas, Attia Lateef, Babar Yasin, Hina Ashraf, Kiran Fatima, Ayesha Javed, Awais Altaf, Syed Zeeshan Haider   +8 more
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