Results 41 to 50 of about 197,785 (174)

Missing the Diagnosis in a Young Woman with Repeated Hospital Admissions: A Case Report

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Missing the diagnosis in a young woman with repeated hospital admissions: a case report Kleine-Levin syndrome (KLS) is a rare sleep disorder characterized by various symptoms, such as recurrent episodes of hypersomnia, cognitive abnormalities ...
Zhe Li   +4 more
doaj   +1 more source

Postmortem Evidence of CRH Neuron Reduction in Narcolepsy Without Cataplexy With Borderline Hypocretin‐1 Levels

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Narcolepsy is classified as type 1 (NT1) or type 2 (NT2) mainly according to hypocretin deficiency rather than cataplexy. While CRH neuron loss in the PVN has been described in NT1, it remains unclear whether similar changes occur in narcolepsy without cataplexy.
Ling Shan   +5 more
wiley   +1 more source

Pharmacological treatment for Kleine-Levin syndrome

open access: yes, 2013
BackgroundThis is an updated version of the original Cochrane review, published in Issue 2, 2009.Kleine-Levin syndrome (KLS) is a rare disorder that mainly affects adolescent men.
Cristiane Conti   +5 more
core   +1 more source

Machine Learning for Diagnosis and Differentiation of Central Disorders of Hypersomnolence: A Systematic Review

open access: yesEuropean Journal of Neurology, Volume 33, Issue 6, June 2026.
This graphical abstract presents the review process (including 41 studies). It highlights the use of machine learning techniques in adults with CDH, such as unsupervised learning for phenotype discovery and supervised learning for diagnosis classification. The figure summarizes the strengths and limitations of each approach, along with key clinical and
Annina Helmy   +8 more
wiley   +1 more source

Sleeping beauty syndrome: A case report and review of female cases reported from India

open access: yesIndian Journal of Psychological Medicine, 2017
Kleine–Levin syndrome (KLS), also called “Sleeping beauty syndrome” is a rare, disorder predominantly reported in adolescent males, characterized by recurrent episodes of hypersomnia and to various degrees, hyperphagia, cognitive disturbances, and ...
Naresh Nebhinani, Navratan Suthar
doaj   +1 more source

A Rare Case of Kleine–Levin Syndrome Following COVID-19

open access: yesAnnals of Internal Medicine: Clinical Cases, 2023
A wide variety of neuropsychiatric manifestations have been reported with COVID-19. We present a case of a 45-year-old man who developed significant hypersomnia and hypersexual thoughts following COVID-19 illness.
Ahmed Maher Shammaa   +2 more
doaj   +1 more source

The PagDMG6341–PagWD40–PagPOLD4 Module Coordinates Base Excision Repair in ‘84K’ Poplar (Populus alba × P. glandulosa)

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 2956-2969, May 2026.
ABSTRACT Base excision repair (BER) is a critical pathway for repairing damaged DNA bases in cells; however, the mechanisms of protein recruitment and interaction in this pathway remain largely unexplored in higher plants. In this study, we used ‘84K’ poplar (Populus alba × P.
Aoyu Ling   +8 more
wiley   +1 more source

Age at Onset and Delays in Diagnosis of Central Disorders of Hypersomnolence Over the Past 30 Years

open access: yesJournal of Sleep Research, Volume 35, Issue 2, April 2026.
ABSTRACT Patients with narcolepsy type 1 (NT1), type 2 (NT2), idiopathic hypersomnia (IH) usually suffer from symptoms for years, even decades, before being diagnosed. We aimed to assess age at onset, age at diagnosis and changes in the diagnostic delays of these patients from 1990 to 2020 in a single centre.
Zhongxing Zhang   +4 more
wiley   +1 more source

Kleine-Levin Syndrome in a Female Patient

open access: yes, 1976
A female patient suffering from Kleine-Levin Syndrome is described. The clinical picture of hypersomnia with compulsive eating, leading to obesity, coupled with a marked change in personality make-up (characterized by episodes of confusion, perplexity ...
Denis Cronin, Lal B. Takrani
core   +1 more source

Síndrome de Kleine-Levin

open access: yes, 2022
Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2022A sonolência é um sintoma comum na população pediátrica. A sua etiologia pode ser multifatorial.
Couto, Ana Miguel Salgueiro da Silva
core   +2 more sources

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