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Kleine-Levin syndrome (KLS) is a rare disorder characterized by discrete episodes of hypersomnia associated with cognitive and behavioural abnormalities, as well as normal alertness and function between episodes. The prevalence of KLS may be underestimated as it is often misdiagnosed and managed as another sleep disorder, neurological disorder or ...
Olufunke, Afolabi-Brown +1 more
core +4 more sources
An Adolescent with Kleine-levin Syndrome: A Case Report [PDF]
Kleine-levin syndrome is characterized as a periodic hypersomnia crisis as well as dietary and variable significant psychic symptoms. This report describes the finding on an evaluation of a 15- year- old girl with KLS.
Pezhman Ghaem-Maghamy +2 more
doaj +3 more sources
An Update on Kleine-Levin Syndrome. [PDF]
Kleine-Levin syndrome (KLS) is a rare relapsing-remitting sleep disorder distinguished by recurrent periods of severe hypersomnia accompanied by cognitive, mood, and behavioral changes. This review focuses mainly on the most recent developments and articles concerning this illness in the preceding five years while attempting to provide a basic overview
Qasrawi SO, BaHammam AS.
europepmc +3 more sources
Proteomic biomarkers of Kleine-Levin syndrome. [PDF]
AbstractStudy ObjectivesKleine–Levin syndrome (KLS) is characterized by relapsing–remitting episodes of hypersomnia, cognitive impairment, and behavioral disturbances. We quantified cerebrospinal fluid (CSF) and serum proteins in KLS cases and controls.MethodsSomaScan was used to profile 1133 CSF proteins in 30 KLS cases and 134 controls, while 1109 ...
Hédou J +15 more
europepmc +4 more sources
Kleine-Levin syndrome in tubercular meningitis
Kleine Levin syndrome is a rare syndrome that involves hypersomnolence, megaphagia and psychiatric disturbances of unknown etiology and pathogenesis.
Thacker Anup +3 more
doaj +1 more source
A Polysomnography Study of Kleine–Levin Syndrome in a Single Center [PDF]
Background: Kleine–Levin syndrome (KLS) is a rare sleep disorder characterized by recurrent episodes of hypersomnia. Polysomnographic (PSG) researches of KLS have been reported only in few publications in the past decades. This study aimed to investigate
Yan-Wen Luo +3 more
doaj +2 more sources
Kleine-Levin syndrome: report of a case with marked dysautonomic features. [PDF]
Kleine-Levin syndrome is a rare neurologic disorder of unknown etiopathogenesis, characterized by abrupt onset and remission of attacks of hypersomnia and cognitive dysfunctions.
Fiamingo G +3 more
europepmc +2 more sources
A strange New Year's Eve: triggers in Kleine-Levin syndrome. [PDF]
International audienceKleine-Levin syndromeis a rare neurological disease of unknown cause beginning typically during adolescence, characterized by remittent-relapsing episodes of severe hypersomnia associated with cognitive and behavioral disturbances ...
Vaillant G +5 more
europepmc +2 more sources
Kleine-Levin syndrome and idiopathic hypersomnia: Spectrum disorders
Kleine-Levin syndrome (KLS) and idiopathic hypersomnia (IH) are primary sleep disorders of unknown etiologies, which often run a chronic course. The common core symptoms of these syndromes are hypersomnolence and sleep drunkenness, with periodic ...
Ravi Gupta +2 more
doaj +2 more sources
A Variant of the Kleine-Levin Syndrome following Head Trauma [PDF]
A 19-year-old man developed the Kleine-Levin syndrome three weeks after the head trauma and subsequent neurosurgical evacuation of right-sided, fronto-temporal epidural hematoma.
V. S. Kostic +3 more
doaj +2 more sources

