Results 191 to 200 of about 12,659 (217)
Hydroa Vacciniforme Lymphoproliferative Disorder With a Truncating KLF2 Variant Presenting as Benign Photodermatoses. [PDF]
Warner-Levy J +3 more
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A transcriptional code controlling fluid shear stress-induced gene expression
Fleisinger L +19 more
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Regulation of KLF2 in the Thymus
The FASEB Journal, 2008Our laboratory has identified the transcription factor Krüppel‐like factor 2 (KLF2) as an important regulator of T cell migration. KLF2 deficient T cells mature normally but are retained in thymus. KLF2 controls the expression of receptors such as S1P 1 and CD62L in T cells. The regulation of
Michael Alexander Weinreich +2 more
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KLF2 regulates neutrophil migration by modulating CXCR1 and CXCR2 in asthma
Neutrophils are key inflammatory cells in the immunopathogenesis of asthma. Neutrophil migration can be initiated through activation of the CXCR1 and CXCR2 receptors by CXC chemokines, such as IL-8. Although transcription factor KLF2 has been found to maintain T cell migration patterns through repression of several chemokine receptors, whether KLF2 can
Zi Wang, Yu-Zhu Li, Ying-Qun Zhu
exaly +3 more sources
Role of KLF2: New insight in inflammatory acne pathogenesis
Journal of Cosmetic Dermatology, 2020AbstractBackgroundAcne is an inflammatory skin condition of pilosebaceous unit. Its pathogenesis is multifactorial with a central role of inflammatory and pro‐inflammatory cytokines mediators. Downregulated Kruppel‐like factor 2 (KLF2) leads to rapid secretion of many cytokines that are involved in acne pathogenesis.AimsThis study aimed at evaluating ...
Menha A. Ibrahim +2 more
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Transcription Factor KLF2 and Its Role in the Regulation of Inflammatory Processes
Biochemistry (Moscow), 2020KLF2 is a member of the Krüppel-like transcription factor family of proteins containing highly conserved DNA-binding zinc finger domains. KLF2 participates in the differentiation and regulation of the functional activity of monocytes, T lymphocytes, adipocytes, and vascular endothelial cells.
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