Results 191 to 200 of about 12,659 (217)

A transcriptional code controlling fluid shear stress-induced gene expression

open access: yes
Fleisinger L   +19 more
europepmc   +1 more source
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Regulation of KLF2 in the Thymus

The FASEB Journal, 2008
Our laboratory has identified the transcription factor Krüppel‐like factor 2 (KLF2) as an important regulator of T cell migration. KLF2 deficient T cells mature normally but are retained in thymus. KLF2 controls the expression of receptors such as S1P 1 and CD62L in T cells. The regulation of
Michael Alexander Weinreich   +2 more
openaire   +1 more source

KLF2 regulates neutrophil migration by modulating CXCR1 and CXCR2 in asthma

open access: yesBiochimica Et Biophysica Acta - Molecular Basis of Disease, 2020
Neutrophils are key inflammatory cells in the immunopathogenesis of asthma. Neutrophil migration can be initiated through activation of the CXCR1 and CXCR2 receptors by CXC chemokines, such as IL-8. Although transcription factor KLF2 has been found to maintain T cell migration patterns through repression of several chemokine receptors, whether KLF2 can
Zi Wang, Yu-Zhu Li, Ying-Qun Zhu
exaly   +3 more sources

Role of KLF2: New insight in inflammatory acne pathogenesis

Journal of Cosmetic Dermatology, 2020
AbstractBackgroundAcne is an inflammatory skin condition of pilosebaceous unit. Its pathogenesis is multifactorial with a central role of inflammatory and pro‐inflammatory cytokines mediators. Downregulated Kruppel‐like factor 2 (KLF2) leads to rapid secretion of many cytokines that are involved in acne pathogenesis.AimsThis study aimed at evaluating ...
Menha A. Ibrahim   +2 more
openaire   +2 more sources

Transcription Factor KLF2 and Its Role in the Regulation of Inflammatory Processes

Biochemistry (Moscow), 2020
KLF2 is a member of the Krüppel-like transcription factor family of proteins containing highly conserved DNA-binding zinc finger domains. KLF2 participates in the differentiation and regulation of the functional activity of monocytes, T lymphocytes, adipocytes, and vascular endothelial cells.
exaly   +3 more sources

KLF2 Regulates Neural Differentiation of Dental Pulp-derived Stem Cells by Modulating Autophagy and Mitophagy

Stem Cell Reviews and Reports, 2023
Hiranmoy Das   +2 more
exaly  

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