Results 151 to 160 of about 54,134 (244)

Histone Modifications in Cardiovascular Disease: Mechanisms and Therapeutic Opportunities

MedComm, Volume 7, Issue 5, May 2026.
This graphical abstract summarizes how classical and emerging histone posttranslational modifications (PTMs), together with their chromatin regulators (writers, erasers, and readers), govern major pathobiological programs in cardiovascular disease.
Yu Zheng, Yu‐Xuan Gao, Mei‐Xing Guo, Li‐Ting Wang, Xiao‐Wen Zheng, Yi‐Hao Liao, Ya Li, Jun‐Ping Zhu, Jia‐Ming Wei   +8 more
wiley   +1 more source

Deconvolution of pro- and antiviral genomic responses in Zika virus-infected and bystander macrophages. [PDF]

, 2018
Genome-wide investigations of host-pathogen interactions are often limited by analyses of mixed populations of infected and uninfected cells, which lower sensitivity and accuracy.
Benner, Christopher, Branche, Emilie, Carlin, Aaron F, Glass, Christopher K, Heinz, Sven, Ley, Klaus, Shresta, Sujan, Suarez-Amaran, Lester, Viramontes, Karla M, Vizcarra, Edward A   +9 more
core  

KLF4 Gene [PDF]

, 2020
openaire   +1 more source

Clinicopathological significance of loss of Y chromosome in male meningiomas

The Journal of Pathology, Volume 269, Issue 1, Page 125-137, May 2026.
Abstract Male meningiomas, comprising approximately 30% of all meningiomas, are more frequently high‐grade and associated with poorer clinical outcomes compared to their female counterparts. Although Y chromosome alterations have been studied in various male‐predominant tumors, a limited number of studies have evaluated their role in meningiomas.
Maki Sakaguchi, Masafumi Horie, Yukinobu Ito, Shingo Tanaka, Hiroko Ikeda, Mitsutoshi Nakada, Akihiko Yoshizawa, Daichi Maeda   +7 more
wiley   +1 more source

EN2 Regulates Pancreatic Cancer Initiation, Progression, and Epithelial‐Mesenchymal Transition Through the Notch Signalling Pathway

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT The incidence and mortality of pancreatic cancer are steadily increasing worldwide, and the disease is projected to become the second leading cause of cancer‐related deaths by 2030. Pancreatic tumorigenesis is driven by multiple genetic alterations, underscoring the need to elucidate the molecular mechanisms underlying pancreatic ...
Wei Yu, Raj K. Varma, Yiming Ma, Varun Chandra Boinpelly, Areej Khatri, Emma Gombos, Rakesh K. Srivastava, Sharmila Shankar   +7 more
wiley   +1 more source

KLF4 wt Allele [PDF]

, 2020
openaire   +1 more source

Deletion of endothelial KLF4 as a model for preeclampsia

Preeclampsia (PE), or gestational hypertension, affects around 5% of pregnancies and leads to approximately 70,000 maternal and 500,000 fetal deaths per year worldwide, with increased cardiovascular and metabolic disease in survivors. PE is associated with elevated circulating levels of the alternative splice isoform of VEGF receptor 1 (sFlt1), defects
Emily Meredith, Andrew T Meredith, Arya Mani, Martin A. Schwartz   +3 more
openaire   +1 more source

KLF4 promotes podocyte differentiation [PDF]

Nature Reviews Nephrology, 2014
openaire   +1 more source

The interaction between virus-bound KLF4 and host-bound PARP1 directs the localization of wild-type adeno-associated virus type 2 (wtAAV2) to cellular sites of DNA damage. [PDF]

J Virol
Abrahams RR, Larsen CIS, Ha R, Majumder K.   +3 more
europepmc   +1 more source

AXL is a novel ERK5/KLF4 target in MEK inhibitor-treated melanoma. [PDF]

Neoplasia
Paudel R, Goller S, Schwarz S, Meder K, Goebeler M, Schmidt M.   +5 more
europepmc   +1 more source