Results 221 to 230 of about 12,957 (269)

The aging choroid plexus and its relationship with gut dysbiosis and Klotho decline: possible intervention strategies. [PDF]

Geroscience
Lai G, Bevilacqua L, Giuliani ME, Bigossi G, Marcozzi S, Casoli T, Abbrescia P, Frigeri A, Malavolta M, Balietti M.   +9 more
europepmc   +1 more source

Table 1_Artesunate alleviates kidney fibrosis by restoring klotho protein and suppressing Wnt/β-catenin signalling pathway.docx

Goran H. Mohammad (15003653), Julius Kieswich (6039776), Abhishek Kumar (156479), Kieran McCafferty (3317427), Ramyangshu Chakraborty (22611512), Christoph Thiemermann (580414), Magdi M. Yaqoob (6518708)   +6 more
openalex   +1 more source

Inflammation-Induced Klotho Deficiency: A Possible Key Driver of Chronic Kidney Disease Progression. [PDF]

Int J Gen Med
Liang Y, Zhang Q, Qian JR, Li SS, Liu QF.   +4 more
europepmc   +1 more source

Inflammation-Driven Molecular Ageing in Chronic Inflammatory Skin Diseases: Is There a Role for Biologic Therapies? [PDF]

Cells
Andrzejczak K, Sternak A, Witkowski W, Ponikowska M.   +3 more
europepmc   +1 more source

Expression of FGF23 and α-KLOTHO in Normal Human Kidney Development and Congenital Anomalies of the Kidney and Urinary Tract (CAKUT). [PDF]

Biomolecules
Bajt P, Racetin A, Kelam N, Pavlović N, Todorović P, Korčulanin MJ, Filipović N, Kuzmić Prusac I, Raguž F, Vukojević K.   +9 more
europepmc   +1 more source

“Long Life” Protein Klotho Powers Remyelination in Mice

Multiple Sclerosis Discovery Forum, 2014
openaire   +1 more source

Association of serum Klotho with tinnitus prevalence, duration and severity: A cross-sectional study in middle-aged and older adults. [PDF]

PLoS One
Du KJ, Mo BY, Hou T, Chen L, Su DR, Yin SH.   +5 more
europepmc   +1 more source

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The Klotho proteins in health and disease

Nature Reviews Nephrology, 2018
The Klotho proteins, αKlotho and βKlotho, are essential components of endocrine fibroblast growth factor (FGF) receptor complexes, as they are required for the high-affinity binding of FGF19, FGF21 and FGF23 to their cognate FGF receptors (FGFRs). Collectively, these proteins form a unique endocrine system that governs multiple metabolic processes in ...
Makoto Kuro-O
exaly   +3 more sources

Klotho Protein and Cardio-Vascular System

Biochemistry (Moscow), 2021
Klotho protein affects a number of metabolic pathways essential for pathogenesis of cardio-vascular diseases and their prevention. It inhibits lipid peroxidation and inflammation, as well as prevents endothelial injury and calcification of blood vessels. Klotho decreases rigidity of blood vessels and suppresses development of the heart fibrosis.
Ivan N, Tyurenkov, Valentina N, Perfilova, Alla A, Nesterova, Yelena, Glinka   +3 more
openaire   +2 more sources