Results 51 to 60 of about 644,059 (295)

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

A prospective randomised control trial comparing functional with mechanical axis alignment in total knee arthroplasty: study protocol for an investigator initiated trial

Trials, 2021
Background A drive to improve functional outcomes for patients undergoing total knee arthroplasty (TKA) has led to alternative alignment being used. Functional alignment (FA) uses intraoperative soft tissue tension to determine the optimal position of ...
Richard Steer, Beth Tippett, R. Nazim Khan, Dermot Collopy, Gavin Clark   +4 more
doaj   +1 more source

Longitudinal Changes in Adiposity After a Youth Sport‐Related Knee Injury: Informing Posttraumatic Osteoarthritis Prevention

Arthritis Care &Research, EarlyView.
Objective Youth who experience a sport‐related knee injury have elevated odds of becoming overweight or developing obesity in 3 to 10 years, compounding their risk for posttraumatic osteoarthritis (PTOA). To inform prevention strategies, this study compared patterns of adiposity change between youth with a sport‐related knee injury and uninjured youth ...
Justin M. Losciale, Nuria E. J. Jansen, Christina Y. Le, Leo Lu, Hui Xie, Marienke van Middelkoop, Jackie L. Whittaker   +6 more
wiley   +1 more source

The Complexity of Human Walking: A Knee Osteoarthritis Study [PDF]

, 2014
This study proposes a framework for deconstructing complex walking patterns to create a simple principal component space before checking whether the projection to this space is suitable for identifying changes from the normality.
Duffell, LD, Faisal, AA, McGregor, AH, Kotti, M, Alison H McGregor, Aldo A Faisal, Lynsey D Duffell, Margarita Kotti, McGregor Alison H., Faisal Aldo A., Kotti Margarita, Duffell Lynsey D.   +11 more
core   +2 more sources

Individuals With Multijoint Osteoarthritis Demonstrate Larger Longitudinal Declines in Frailty: Data From the Canadian Longitudinal Study on Aging

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to test the hypothesis that multijoint osteoarthritis would modify the relation between time and frailty progression, in which more affected joints would lead to larger declines over six years compared to those without osteoarthritis using data from the Canadian Longitudinal Study on Aging.
Carson Halliwell, Rebecca Moyer, Myles W. O'Brien   +2 more
wiley   +1 more source

Joint loading asymmetries in knee replacement patients observed both pre- and six months post-operation

BackgroundStudies have highlighted asymmetries in knee joint moments during activities of daily living in individuals with osteoarthritis and joint replacements.
Stokes, M., Taylor, M., Worsley, Peter, Barrett, D.S.   +3 more
core   +1 more source

Clinical effectiveness of a rehabilitation program integrating exercise, self-management, and active coping strategies for chronic knee pain: a cluster randomized trial [PDF]

, 2007
OBJECTIVE: Chronic knee pain is a major cause of disability and health care expenditure, but there are concerns about efficacy, cost, and side effects associated with usual primary care. Conservative rehabilitation may offer a safe, effective, affordable
Jones, R. H., Williamson, Elizabeth, Pimm, T.J., Mitchell, H. L., Dieppe, P. A., Walsh, NE, Pimm, TJ, Mitchell, Helene, Patel, A., Dieppe, PA, T. J. Pimm, N. E. Walsh, Hurley, Mike, Jones, R.H., Hurley, MV, Walsh, N. E., B. C. Reeves, Reeves, BC, Mitchell, H., Dieppe, P.A., Jones, RH, P. A. Dieppe, Dieppe, Paul, Hurley, Michael, Pimm, T. J., Hurley, M. V., Walsh, N.E., H. L. Mitchell, A. Patel, Patel, Anita, Patel, A, Reeves, Barney, Walsh, Nicola, Williamson, E, Pimm, J., Jones, Roger, M. V. Hurley, E. Williamson, Mitchell, H.L., Reeves, B. C., R. H. Jones, Mitchell, HL, Williamson, E., Reeves, B.C., Pimm, John   +44 more
core   +1 more source

Molecular diagnostics for perioperative microbial identification in periprosthetic joint infection: A scoping review and proposal of a diagnostic flow chart

Journal of Experimental Orthopaedics
Purpose Periprosthetic joint infections (PJI) are among the most feared complications of joint reconstruction. Unfortunately, traditional cultures often fail to identify the aetiological agents of PJI.
Pier Francesco Indelli, Trifon Totlis, Bruno Lovreković, Michael Engl, Bruno Violante, Pawel Skowronek, Guillaume Demey, Stefano Ghirardelli, Chiara Maci, Antonella Castagna, Laura Schianchi, Chiara Tassan Din, James Harty, Goksel Dikmen, Christian Schaller, Marko Ostojić   +15 more
doaj   +1 more source

How often do we alter constitutional limb alignment, joint line obliquity, and Coronal Plane Alignment of the Knee (CPAK) phenotype when performing mechanically aligned TKA?: a large single-institution retrospective radiological analysis

Bone & Joint Open
Aims: While mechanical alignment (MA) is the traditional technique in total knee arthroplasty (TKA), its potential for altering constitutional alignment remains poorly understood.
Luke E. Corban, Victor A. van de Graaf, Darren B. Chen, Jil A. Wood, Ashish D. Diwan, Samuel J. MacDessi   +5 more
doaj   +1 more source

Proximal fibular resection improves knee biomechanics and enhances tibial stress fracture healing in patients with osteoarthritis with varus deformity: a prospective, randomized control analysis

Arthroplasty, 2020
Background The present study aimed to evaluate the functional outcome of single-stage total knee arthroplasty using long-stem tibial component with proximal fibular resection (PFR) for patients with knee osteoarthritis with varus deformity associated ...
Vikram Indrajit Shah, Sachin Upadhyay, Kalpesh Shah, Ashish Sheth, Amish Kshatriya, Jayesh Patil   +5 more
doaj   +1 more source