Results 51 to 60 of about 231,410 (313)

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Radiographic assessment of knee-ankle alignment after total knee arthroplasty for varus and valgus knee osteoarthritis

, 2017
Background: There are unanswered questions about knee-ankle alignment after total knee arthroplasty (TKA) for varus and valgus osteoarthritis (OA) of the knee. The aim of this retrospective study was to assess knee-ankle alignment after TKA.
Sun, Wei, Wang, Weiguo, Ma, Jinhui, Gao, Fuqiang, Guo, Wanshou, Li, Zirong   +5 more
core   +1 more source

The Warwick patellofemoral arthroplasty trial : a randomised clinical trial of total knee arthroplasty versus patellofemoral arthroplasty in patients with severe arthritis of the patellofemoral joint [PDF]

, 2011
Background Severe arthritis of the knee is a disabling condition, with over 50,000 knee replacements performed each year in the UK. Isolated patellofemoral joint arthritis occurs in over 10% of these patients with the treatment options being ...
Costa, Matthew L., Tim Spalding, Parsons, Nicholas R., Spalding, Tim, Achten, Juul, McGuinness, Katie, Nick Parsons, Parsons Nick, Spalding Tim, Matthew Costa, Achten Juul, Michelle Odumenya, McGuinness Katie, Odumenya, M. (Michelle), Katie McGuinness, Odumenya Michelle, Costa Matthew, Juul Achten   +17 more
core   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

Arthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King, Alanna Weisman, Baiju R. Shah, Robert Goldberg, Amish Parikh, Ian Stanaitis, Vivian Hung, Rosane Nisenbaum, Abdalmohsen Almodahka, Lorraine Lipscombe, Gillian A. Hawker   +10 more
wiley   +1 more source

Dynamic knee joint mechanics after anterior cruciate ligament reconstruction.

, 2014
There is a scarcity of information on the long term adaptations in lower limb biomechanics during game specific movements after an anterior cruciate ligament (ACL) reconstruction.
Harrison, Andrew, Andrew J. Harrison, Sarah Breen (3923378), Kenny, Ian, Harrison, Andrew J., Kenny, IC, Ian C. Kenny (10230734), Ian C. Kenny, Sarah Clarke, Breen, Sarah, Clarke, Sarah B, Sarah Clarke (6337823), Kenny, Ian C., Andrew J. Harrison (7239119), Clarke, Sarah, Clarke, SB, Harrison, AJ   +16 more
core   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Computer assisted knee replacement surgery : is the movement mainstream?

, 2014
The first computer-assisted Total Knee Arthroplasty (TKA) was performed in 1997. The FDA approved computer assisted knee arthroplasty systems used in the early 2000s.
Deep, Kamal, Clarke, Jon, Picard, Frederic, Gregori, Alberto   +3 more
core   +1 more source

The effect of patient age at intervention on risk of implant revision after total replacement of the hip or knee: a population-based cohort study

The Lancet, 2017
Summary Background Total joint replacements for end-stage osteoarthritis of the hip and knee are cost-effective and demonstrate significant clinical improvement.
L. Bayliss, D. Culliford, A Paul Monk, S. Glyn-Jones, D. Prieto-Alhambra, A. Judge, C. Cooper, Andrew Carr, Nigel K. Arden, David J Beard, A. Price   +10 more
semanticscholar   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles, Hannah F. Brubeck, Adrienne D. Tanus, Courtney N. Loecker, Punyasha Roul, Bryant R. England, Elizabeth R. Wahl, James S. Andrews, Namrata Singh, Joshua F. Baker, Patricia P. Katz, Dolores M. Shoback, Jose M. Garcia, Ariela R. Orkaby, Katherine D. Wysham   +14 more
wiley   +1 more source

Knee pain [PDF]

, 2006
JC is a 13 year old boy who presented with a 3 week history of anterior right knee pain. Pain is activity related and brought on whenever JC plays football or basketball. He never needed to stop from any particular activity because of the pain.
Formosa, Aaron
core