Results 131 to 140 of about 246,658 (352)

Optimizing biophysical properties of cellular niches to enhance stem cell‐derived extracellular vesicle function in musculoskeletal regeneration

open access: yesBMEMat, EarlyView.
Extracellular vesicles (EVs) derived from stem cells show promise for applications in regenerative medicine, but their scalability and yield remain challenges. This review explores the approaches for biophysical modulations within cell niches on EV properties, discusses the current clinical application of EVs, and provides an outlook on the existing ...
Yang Xu   +9 more
wiley   +1 more source

Learning-Based Cost Functions for 3D and 4D Multi-Surface Multi-Object Segmentation of Knee MRI: Data from the Osteoarthritis Initiative

open access: yes, 2018
A fully automated knee MRI segmentation method to study osteoarthritis (OA) was developed using a novel hierarchical set of random forests (RF) classifiers to learn the appearance of cartilage regions and their boundaries.
Kashyap, Satyananda   +3 more
core   +1 more source

Histopathologic Analysis of the Morpho‐Functional Zones of the Human Acetabular Labrum

open access: yesClinical Anatomy, EarlyView.
ABSTRACT The structural and functional adaptation of soft tissues to mechanical load controls their ability to withstand injury and influences their capacity for healing. Similar to the knee meniscus, the acetabular labrum exhibits zonal differences in mechanical load distribution, resulting in distinct regions with unique structural and functional ...
Abdulaziz A. Alomiery   +4 more
wiley   +1 more source

Pathogenesis and potential therapeutic targets of trichorhinophalangeal syndrome; lessons obtained from animal studies

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Trichorhinophalangeal syndrome (TRPS) is a rare genetic disease inherited in an autosomal dominant manner. It occurs in 1 in 100,000 people globally and is caused by several types of mutations of the TRPS1 gene. Since the first human patient was reported in 1966, typical and atypical pathologies, disease courses, and treatment case ...
Naoya Saeki   +6 more
wiley   +1 more source

The influence of osteoporosis on varus osteoarthritis of the knee [PDF]

open access: bronze, 1998
Masanori Terauchi   +4 more
openalex   +1 more source

Targeted Ruthenium‐Based Anti‐Inflammatory Nanoagent for Enhanced Rheumatoid Arthritis Treatment

open access: yesExploration, EarlyView.
The inhibition of joint synovial inflammation, caused by poor oxygen (O2) supply and excessive reactive oxygen species (ROS) generation, is an important treatment strategy for rheumatoid arthritis (RA). A targeted ruthenium‐based anti‐inflammatory nanosystem (RuFOMs‐FA) based of ultra‐small ruthenium clusters‐loaded F127‐organosilica micelles with ...
Ziwei Zhao   +8 more
wiley   +1 more source

Assessment of Foot Deformities in Patient with Knee Osteoarthritis

open access: yesAl-Khawarizmi Engineering Journal
Foot morphology evaluation techniques are commonly used to evaluate foot abnormalities. The foot is essential for keeping the biomechanical performance of the lower extremities.
Ruba Musaid   +2 more
doaj   +1 more source

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