Results 131 to 140 of about 146,043 (313)

The EXPLAIN Study: Exploring Arthrogryposis Multiplex Congenita in Adults in Norway — A Description of Demographic, Medical, and Neurological Findings

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen, Kristin Ørstavik, Unni Steen, Mathias Toft, Cathrine Brunborg, Lena Lande Wekre   +5 more
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Exploring the causal link among statin drugs and the osteoarthritis risk based on Mendelian randomization research

Frontiers in Genetics
PurposeStatins may have a protective effect against osteoarthritis (including knee osteoarthritis and hip osteoarthritis); however, the link between statins and osteoarthritis risk is incompletely established.
Wenjie Chen, Zhi Sun, Xinhai Xiong, Haitao Tan, Junhao Hu, Chenrui Liu, Cheng Chen   +6 more
doaj   +1 more source

Continuous Sewing Machine‐Like Suture Provides Higher Failure and Yield Load Compared to Traditional Techniques for Meniscal Root Repair in a Biomechanical Porcine Model

Arthroscopy, EarlyView.
Purpose To evaluate the biomechanical performance of the sewing machine‐like suture (SMS) technique against three established techniques (two cinch‐loop (TCL), modified Mason‐Allen (MMA), and double Mason‐Allen (DMA)) for transtibial pull‐out repair of posterior medial meniscal root tear (PMMRT) in a porcine model.
Yizhong Peng, Wenbo Yang, Yi Li, Chunqing Meng, Hong Wang, Wei Huang   +5 more
wiley   +1 more source

Nontobacco Nicotine Dependence Is Associated With Perioperative Complications and Repeat Surgery After Arthroscopic Rotator Cuff Repair

Arthroscopy, EarlyView.
Purpose To compare perioperative complications and revision surgery rates between following primary rotator cuff repair among patients with nontobacco nicotine dependence (NTND), no nicotine dependence, and traditional tobacco‐related nicotine dependence.
Samuel A. Florentino, Alexander N. Berk, Logan M. Good, Jeremy M. Adelstein, Robert J. Wetzel, George Ochenjele, Joshua K. Napora   +6 more
wiley   +1 more source

STRIDE LENGTH AND ITS CORRELATION WITH DYNAMIC BALANCE IN THE ELDERLY WITH KNEE OSTEOARTHRITIS

Journal of Vocational Health Studies
Background: Patients with knee osteoarthritis experience postural changes that impair balance control due to frequent shifts in the Center of Gravity (COG). Individuals who experience knee osteoarthritis tend to experience a decrease in stride length.
Nikmatur Rosidah, Raray Inas Prianggalistiari, Anita Faradilla Rahim, Bayu Prastowo   +3 more
doaj   +1 more source

Healing Integrity Determines Meniscal Extrusion After Isolated Medial Meniscus Posterior Root Repair in Knees With No Lower Limb Malalignment

Arthroscopy, EarlyView.
Purpose To investigate changes in meniscal extrusion and meniscal healing status following root repair, and the relationship between meniscal extrusion and healing conditions. Methods Patients who underwent isolated root repair between 2019 and 2023 and consented to undergo second‐look arthroscopy to evaluate their healing condition (1 year ...
Jin Seong Kim, Ui Jae Hwang, Chang Woo Woo, Choong Hyeok Choi, Kyu Sung Chung   +4 more
wiley   +1 more source

Computed Tomography‐Based Morphometric Analysis Reveals Intercondylar Notch Stenosis and Osteophytes Are Associated With Anterior Cruciate Ligament Injury

Arthroscopy, EarlyView.
Purpose To quantitatively assess intercondylar notch morphometrics using 3‐dimensional computed tomography reconstruction, evaluate their association with anterior cruciate ligament (ACL) injury in Asian populations, and investigate the prevalence of osteophytes in patients with ACL injury.
Xiaozhong Ma, WenMing Jiang, Chao Lu, Tongyue Ji, Su Yan, Heng Zhu, Xue He, Hao Shu, Lei Wang, Luning Sun   +9 more
wiley   +1 more source

Quantitative ultrasound assessment of gastrocnemius muscle changes in patients with knee osteoarthritis

Journal of International Medical Research
Background Knee osteoarthritis presents with posterior knee pain, stiffness, and restricted mobility, potentially affecting periarticular muscle biomechanics.
Hui Zuo, Ting Xu, Qianwen Wang, Wei Tan, Xu Liu   +4 more
doaj   +1 more source

Small but Significant Effect on Patellar Height and Tibial Tuberosity‐Trochlear Groove Distance Following Ascending Versus Descending Tibial Tubercle Osteotomy in Medial Open‐Wedge High Tibial Osteotomy

Arthroscopy, EarlyView.
Purpose To compare radiographic patellofemoral characteristics following ascending tibial tubercle (AT) and descending tibial tubercle (DT) medial open‐wedge high tibial osteotomy (OWHTO). Methods This retrospective single‐center study included all patients who underwent AT‐OWHTO or DT‐OWHTO between October 2014 and December 2022 with complete ...
Matthias Biner, Jakob Ackermann, Sandro Hodel, Sandro F. Fucentese, Lazaros Vlachopoulos, Lukas Jud   +5 more
wiley   +1 more source