Results 111 to 120 of about 8,444 (194)
Lasers in Surgery and Medicine, EarlyView.ABSTRACT Objectives Perforated appendicitis commonly results in intra‐abdominal infection requiring prolonged antibiotic therapy. Intraoperative antimicrobial adjuncts are limited, and photodynamic therapy (PDT) may provide a targeted, resistance‐independent approach.
Timothy M. Baran +7 more
wiley +1 more source
A Knob-Socket Based Rule Set for Designing Peptide Binding to PDZ Domains [PDF]
Biophysical Journal, 2018 Shivarni Patel, Hyun Joo, Jerry Tsai
openaire +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT Top‐down proteomics (TDP) characterizes proteoforms in cells, tissues, and biofluids, in discovery mode and on a global scale, requiring analytical tools with high peak capacity for proteoform separation and high sensitivity for proteoform detection, given the extremely high proteoform complexity and wide proteoform concentration dynamic range.
Guijie Zhu +5 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Small, EarlyView.Pulse‐duration‐controlled ultra‐short laser processing is shown to directly create binder‐free Fe‐enriched NiOx electrodes with tunable porosity, active‐site density, and oxygen‐evolution kinetics. Shorter pulses generate defect‐rich nanostructures that accelerate charge transfer, promote highly active NiFeOOH formation, and deliver durable alkaline ...
Sandra Susan Koshy +2 more
wiley +1 more source
High Voltage, EarlyView.ABSTRACT To address the issue of low detection accuracy for zero‐value insulators in distribution lines, this study proposes a novel method for detecting these insulators based on the electroluminescence effect. Through theoretical analysis and experimentation, it was found that the luminescence intensity of ZnS:Cu electroluminescent material varies ...
Jianghai Geng +6 more
wiley +1 more source
The septin cytoskeleton is required for plasma membrane repair
EMBO ReportsPlasma membrane repair is a fundamental homeostatic process of eukaryotic cells. Here, we report a new function for the conserved cytoskeletal proteins known as septins in the repair of cells perforated by pore-forming toxins or mechanical disruption ...
M Isabella Prislusky +9 more
doaj +1 more source
Acta Zoologica, EarlyView.ABSTRACT The marine shrimp of the genus Typton are widely distributed, known to be associated with sessile organisms such as sponges. Information about this genus is limited, highlighting the scarcity of important features in its biology, including larval forms.
Matheus Sene +2 more
wiley +1 more source
Boreas, EarlyView.Rapid thaw of the Earth's cryosphere in response to anthropogenic warming highlights the need to identify and understand the contrasting signatures of past ice‐sheet stability and collapse. The Kvarken archipelago, western Finland, at the centre of the former Fennoscandian Ice Sheet (FIS), has been designated a UNESCO World Heritage site in recognition
Niko Putkinen +6 more
wiley +1 more source
A Real‐Time Multi‐Scale Neural Representation for Complex Surface Reflectance
Computer Graphics Forum, EarlyView.Abstract Recent machine learning methods have significantly advanced the state of the art in the classic problem of representing surface appearance over angle, space, and scale. The models tend, however, to be relatively heavy compared to traditional fixed‐function representations, making real‐time application challenging.
Heikki Timonen +2 more
wiley +1 more source