Results 121 to 130 of about 1,849,891 (275)

Probing Type‐II Multiferroicity in Monolayer NiBr2

Advanced Science, EarlyView.
Type‐II multiferroicity is demonstrated in monolayer NiBr2. Scanning tunneling microscopy resolves ferroelectric polarization arising from non‐collinear magnetic order, and reciprocal control with electric and magnetic fields confirms intrinsic magnetoelectric coupling.
Aleš Cahlík, Antti Karjasilta, Anshika Mishra, Robert Drost, Mohammad Amini, Javaria Arshad, Büşra Gamze Arslan, Peter Liljeroth   +7 more
wiley   +1 more source

Intracellular cholesterol trafficking is dependent upon NPC2 interaction with lysobisphosphatidic acid

eLife, 2019
Unesterified cholesterol accumulation in the late endosomal/lysosomal (LE/LY) compartment is the cellular hallmark of Niemann-Pick C (NPC) disease, caused by defects in the genes encoding NPC1 or NPC2.
Leslie A McCauliff, Annette Langan, Ran Li, Olga Ilnytska, Debosreeta Bose, Miriam Waghalter, Kimberly Lai, Peter C Kahn, Judith Storch   +8 more
doaj   +1 more source

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

Advanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic, Zachary M. Geisterfer, Akshita Chhabra, Vladimir M. Jovanovic, Ian Seim, Christian Hoffmann, Antonela Condric, Gerard Aguilar Pérez, Rinse de Boer, Lars T. Hofstede, Jingao Sun, Kiara Freitag, Katja Nowick, Marina Jendrach, Frank L. Heppner, Vladimir Despic, Michaela Müller‐McNicoll, Stephan Sigrist, Geert van den Bogaart, Sofiia Reshetniak, Amy S. Gladfelter, Dragomir Milovanovic   +21 more
wiley   +1 more source

Kinkless Electronic Junction along 1D Electronic Channel Embedded in a Van Der Waals Layer

Advanced Science
Here, the formation of type‐I and type‐II electronic junctions with or without any structural discontinuity along a well‐defined 1 nm‐wide 1D electronic channel within a van der Waals layer is reported.
Qirong Yao, Jae Whan Park, Choongjae Won, Sang‐Wook Cheong, Han Woong Yeom   +4 more
doaj   +1 more source

Structure and Analysis of R1 and R2 Pyocin Receptor-Binding Fibers

Viruses, 2018
The R-type pyocins are high-molecular weight bacteriocins produced by some strains of Pseudomonas aeruginosa to specifically kill other strains of the same species.
Sergey A. Buth, Mikhail M. Shneider, Dean Scholl, Petr G. Leiman   +3 more
doaj   +1 more source

Multimerization of Adenovirus Serotype 3 Fiber Knob Domains Is Required for Efficient Binding of Virus to Desmoglein 2 and Subsequent Opening of Epithelial Junctions

Journal of Virology, 2011
ABSTRACT Recently, we identified desmoglein 2 (DSG2) as the main receptor for a group of species B adenoviruses (Ads), including Ad3, a serotype that is widely distributed in the human population (H. Wang et al., Nat. Med. 17: 96–104, 2011).
Hongjie, Wang, ZongYi, Li, Roma, Yumul, Stephanie, Lara, Akseli, Hemminki, Pascal, Fender, André, Lieber   +6 more
openaire   +3 more sources

Quantum‐Trained AI Enables Inverse Design of Organic Frontier Orbitals at Billion‐Scale

Advanced Science, EarlyView.
Quantum‐trained AI links molecular substructures to frontier‐orbital energetics and enables interpretable screening across nearly one billion GDB‐13 molecules. By combining fragment‐ and ring‐level insights with donor–acceptor energy alignment against ITIC, the framework narrows an immense chemical space to a small set of promising candidates and ...
Yeongnam Ko, Se Jin Kim, Ki Chul Kim
wiley   +1 more source

Targeting of Adenovirus to Endothelial Cells by a Bispecific Single-Chain Diabody Directed against the Adenovirus Fiber Knob Domain and Human Endoglin (CD105)

Molecular Therapy, 2001
The use of adenoviruses for antivascular cancer gene therapy is limited by their low transduction efficiency for endothelial cells. We have developed a recombinant bispecific antibody as a molecular bridge, linking the adenovirus capsid to the endothelial cell surface protein endoglin, for vascular targeting of adenoviruses.
Nettelbeck, Dirk M., Miller, Daniel W., Jérôme, Valérie, Zuzarte, Marylou, Watkins, Sarah J., Hawkins, Robert E., Müller, Rolf, Kontermann, Roland E.   +7 more
openaire   +2 more sources

Probabilistic Computing via Gate‐Tunable Random Telegraph Noise

Advanced Science, EarlyView.
Intrinsic random telegraph noise in metal–oxide–semiconductor field‐effect transistors is harnessed to create gate‐tunable probabilistic bits. By modulating carrier‐trapping dynamics, the device produces stochastic binary outputs with a continuous bias‐to‐probability transfer.
Gyungwon Yun, Jin Pyo Kang, Ho‐Sung Lee, Ik‐Hyeon Jeon, Ki‐Ju Park, Won‐Ju Cho, Seung‐heon Chris Baek, Joo‐Hyung Chae, Hamin Park   +8 more
wiley   +1 more source

Structure of apolipoprotein B-100 in low density lipoproteins

Journal of Lipid Research, 2001
There is general consensus that amphipathic α-helices and β sheets represent the major lipid-associating motifs of apolipoprotein (apo)B-100. In this review, we examine the existing experimental and computational evidence for the pentapartite domain ...
Jere P. Segrest, Martin K. Jones, Hans De Loof, Nassrin Dashti   +3 more
doaj   +1 more source