Mapping structural constraints and adaptive potential in a capsule-degrading phage tailspike protein. [PDF]
Evert S +4 more
europepmc +1 more source
Low Vision Assessment in Virtual Reality (LVAVR): Spatial Computing in Virtual Reality and Real-World. [PDF]
Bailey E +4 more
europepmc +1 more source
Isospora atticorae n. sp. (Apicomplexa: Eimeriidae) from the white-thighed swallow Atticora tibialis (Cassin, 1853) (Passeriformes: Passeri: Hirundinidae) in Brazil. [PDF]
Dorna-Santos L +5 more
europepmc +1 more source
A tri-specific EGFR/cMet/VEGF antibody demonstrates potent multi-mechanistic activity in preclinical triple-negative breast cancer models. [PDF]
Pu P +13 more
europepmc +1 more source
Compositionally Biased Regions Within Structured Protein Domains. [PDF]
Harrison PM.
europepmc +1 more source
Engineered interfaces in Rac1 and Cdc42 biosensors enhance sensitivity and reduce cell perturbation. [PDF]
Marston DJ +10 more
europepmc +1 more source
Designing a vaccine candidate against egg drop syndrome virus: an <i>in silico</i> approach. [PDF]
Najafian J +2 more
europepmc +1 more source
The Chemical Synthesis of Knob Domain Antibody Fragments [PDF]
Cysteine-rich knob domains found in the ultralong complementarity determining regions of a subset of bovine antibodies are capable of functioning autonomously as 3-6 kDa peptides. While they can be expressed recombinantly in cellular systems, in this paper we show that knob domains are also readily amenable to a chemical synthesis, with a co-crystal ...
Sebastian Kelm +2 more
exaly +6 more sources
Biodistribution of radioiodinated adenovirus fiber protein knob domain after intravenous injection in mice. [PDF]
ABSTRACT The knob domains from the fiber proteins of adenovirus serotypes 2 and 12 were labeled with radioiodine and then injected into the bloodstreams of mice. Knob proteins with functional binding sites for the coxsackie and adenovirus receptor (CAR) were cleared rapidly from the circulation, with radioactivity appearing ...
Vibhudutta Awasthi +2 more
exaly +3 more sources
Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli. [PDF]
The adenovirus fiber protein is used for attachment of the virus to a specific receptor on the cell surface. Structurally, the protein consists of a long, thin shaft that protrudes from the vertex of the virus capsid and terminates in a globular domain termed the knob. To verify that the knob is the domain which interacts with the cellular receptor, we
Johann Deisenhofer, Robert D Gérard
exaly +3 more sources

