Results 241 to 250 of about 1,849,891 (275)

Low Vision Assessment in Virtual Reality (LVAVR): Spatial Computing in Virtual Reality and Real-World. [PDF]

open access: yes2026 IEEE Conf Virtual Real 3D User Interfaces Abstr Workshops (2026)
Bailey E   +4 more
europepmc   +1 more source

A tri-specific EGFR/cMet/VEGF antibody demonstrates potent multi-mechanistic activity in preclinical triple-negative breast cancer models. [PDF]

open access: yesJ Biol Chem
Pu P   +13 more
europepmc   +1 more source

Engineered interfaces in Rac1 and Cdc42 biosensors enhance sensitivity and reduce cell perturbation. [PDF]

open access: yesMol Biol Cell
Marston DJ   +10 more
europepmc   +1 more source

The Chemical Synthesis of Knob Domain Antibody Fragments [PDF]

open access: yesACS Chemical Biology, 2021
Cysteine-rich knob domains found in the ultralong complementarity determining regions of a subset of bovine antibodies are capable of functioning autonomously as 3-6 kDa peptides. While they can be expressed recombinantly in cellular systems, in this paper we show that knob domains are also readily amenable to a chemical synthesis, with a co-crystal ...
Sebastian Kelm   +2 more
exaly   +6 more sources

Biodistribution of radioiodinated adenovirus fiber protein knob domain after intravenous injection in mice. [PDF]

open access: yesJournal of Virology, 2004
ABSTRACT The knob domains from the fiber proteins of adenovirus serotypes 2 and 12 were labeled with radioiodine and then injected into the bloodstreams of mice. Knob proteins with functional binding sites for the coxsackie and adenovirus receptor (CAR) were cleared rapidly from the circulation, with radioactivity appearing ...
Vibhudutta Awasthi   +2 more
exaly   +3 more sources

Characterization of the knob domain of the adenovirus type 5 fiber protein expressed in Escherichia coli. [PDF]

open access: yesJournal of Virology, 1994
The adenovirus fiber protein is used for attachment of the virus to a specific receptor on the cell surface. Structurally, the protein consists of a long, thin shaft that protrudes from the vertex of the virus capsid and terminates in a globular domain termed the knob. To verify that the knob is the domain which interacts with the cellular receptor, we
Johann Deisenhofer, Robert D Gérard
exaly   +3 more sources

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