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Knockdown of UGT352A5 decreases the thiamethoxam resistance in Bemisia tabaci (Hemiptera: Gennadius)
International Journal of Biological Macromolecules, 2021Uridine diphosphate (UDP)-glycosyltransferases (UGTs), which are major phase II detoxification enzymes, have been implicated in the glycosylation of lipophilic endobiotics and xenobiotics and thus potentially lead to the evolution of insecticide resistance. In this study, we identified and cloned two putative UGT genes from transcriptome data which are
Tianhua, Du +14 more
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Knockdown of LMW-PTP enhances stress resistance in Caenorhabditis elegans
International Journal of Biological Macromolecules, 2018Low molecular weight protein tyrosine phosphatase (LMW-PTP) is highly conserved across almost all living organisms and is involved in the modulation of a number of cellular proteins related to important signaling pathways. In this study, we isolated lmwptp (Y94H6A.7) of Caenorhabditis elegans, the homolog of human ACP1, and set up an effective feeding ...
Lin, Zhou +6 more
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Novel knockdown resistance mutations in human lice: artifacts or emerging resistance?
Trends in ParasitologyAn exceptionally high number of novel mutations within domain II of the voltage-gated sodium channel have been reported in human lice from Iran and Saudi Arabia. We critically evaluate these reports, highlighting that many of them may be methodological artifacts, and urge rigorous confirmation before assigning biological significance.
Om P. Singh +2 more
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Pesticide Biochemistry and Physiology, 1998
Abstract A resistant strain of Helicoverpa armigera selected by cyhalothrin was used to investigate the relative importance of knockdown resistance ( kdr ) for different levels of resistance to cyhalothrin and fenvalerate and the inheritance of kdr to fenvalerate.
Lijun Ru +3 more
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Abstract A resistant strain of Helicoverpa armigera selected by cyhalothrin was used to investigate the relative importance of knockdown resistance ( kdr ) for different levels of resistance to cyhalothrin and fenvalerate and the inheritance of kdr to fenvalerate.
Lijun Ru +3 more
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X‐linked QTL for knockdown resistance to high temperature in Drosophila melanogaster
Insect Molecular Biology, 2007Abstract Knockdown Resistance to High Temperature (KRHT) is an adaptive trait of thermotolerance in insects. An interval mapping was performed on chromosome X of Drosophila melanogaster to search for quantitative trait loci (QTL) affecting KRHT.
Norry, F. M. +4 more
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Sodium channel neurotoxins as probes of the knockdown resistance mechanism.
Neurotoxicology, 1986A simple paralysis bioassay was used to measure the effects of sodium channel blockers and activators on third instar larvae of three strains of the house fly, Musca domestica. The pyrethroid-resistant strains kdr and super-kdr, which are thought to have rediced neural sensitivity to pyrethroids, displayed 28-fold and greater than 909-fold resistance ...
J R, Bloomquist, T A, Miller
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Molecular mechanism of knockdown resistance to pyrethroid insecticides
Acta Horticulturae, 2017Y. Du, Y. Nomura, B.S. Zhorov, K. Dong
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The Molecular Mechanism of Knockdown Resistance
2001David M. Soderlund +4 more
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