Results 101 to 110 of about 406,670 (317)
Conditional inactivation of PDCD2 induces p53 activation and cell cycle arrest
Biology Open, 2014 PDCD2 (programmed cell death domain 2) is a highly conserved, zinc finger MYND domain-containing protein essential for normal development in the fly, zebrafish and mouse. The molecular functions and cellular activities of PDCD2 remain unclear.
Celine J. Granier +6 more
doaj +1 more source
Mice and Covert Channels [PDF]
arXiv, 2019 Any secure network is only as secure as its weakest component. With overt channels tightly secured and attackers have started focusing on optical, audible, magnetic, and thermal covert channels to access sensitive systems. In this paper, we present a novel, reliable and bidirectional optical covert channel which uses optical mice.
arxiv
Molecular Oncology, EarlyView.Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger +2 more
wiley +1 more source
In vivo blood flow abnormalities in the transgenic knockout sickle cell mouse [PDF]
, 1999 Stephen H. Embury +4 more
openalex +1 more source
MIF as an oncogenic driver of low‐heterogeneity melanomas
Molecular Oncology, EarlyView.Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran +4 more
wiley +1 more source
Undirected Cat-and-Mouse is P-complete [PDF]
arXiv, 2015 Cat-and-mouse is a two-player game on a finite graph. Chandra and Stockmeyer showed cat-and-mouse is P-complete on directed graphs. We show cat-and-mouse is P-complete on undirected graphs. To our knowledge, no proof of the directed case was ever published. To fill this gap we give a proof for directed graphs and extend it to undirected graphs.
arxiv
Transgenic knockout mice exclusively expressing human hemoglobin S after transfer of a 240-kb β s -globin yeast artificial chromosome: A mouse model of sickle cell anemia [PDF]
, 1998 Judy C. Chang +10 more
openalex +1 more source
Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Predicting video saliency using crowdsourced mouse-tracking data [PDF]
arXiv, 2019 This paper presents a new way of getting high-quality saliency maps for video, using a cheaper alternative to eye-tracking data. We designed a mouse-contingent video viewing system which simulates the viewers' peripheral vision based on the position of the mouse cursor.
arxiv
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Molecular Oncology, EarlyView.Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source