Results 151 to 160 of about 406,670 (317)

Morphological analysis of endocytosis in efferent ductules of estrogen receptor‐α knockout male mouse [PDF]

open access: bronze, 2001
Masaaki Nakai   +8 more
openalex   +1 more source

Associations of Cerebrospinal Fluid Orexin‐A, Alzheimer Disease Biomarkers, and Cognitive Performance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACTObjectiveCerebrospinal fluid (CSF) orexin‐A has been suggested to be a biomarker of Alzheimer disease (AD). In both cognitively unimpaired healthy older adults and individuals with symptomatic AD, CSF orexin‐A is positively associated with CSF Aβ42, p‐tau181, and total tau (t‐tau) concentrations.
Ruijin Lu   +13 more
wiley   +1 more source

TENT5-mediated polyadenylation of mRNAs encoding secreted proteins is essential for gametogenesis in mice

open access: yesNature Communications
Cytoplasmic polyadenylation plays a vital role in gametogenesis; however, the participating enzymes and substrates in mammals remain unclear. Using knockout and knock-in mouse models, we describe the essential role of four TENT5 poly(A) polymerases in ...
Michał Brouze   +11 more
doaj   +1 more source

Immune Phenotypic Characterization of a TRAIL-Knockout Mouse. [PDF]

open access: yesCancers (Basel), 2023
Stoyanova AK   +9 more
europepmc   +1 more source

Unleashing the Power of Multiomics: Unraveling the Molecular Landscape of Peripheral Neuropathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Peripheral neuropathies (PNs) affect over 20 million individuals in the United States, manifesting as a wide range of sensory, motor, and autonomic nerve symptoms. While various conditions such as diabetes, metabolic disorders, trauma, autoimmune disease, and chemotherapy‐induced neurotoxicity have been linked to PN, approximately one‐third of
Julie Choi   +7 more
wiley   +1 more source

Deregulated Transcription and Proteostasis in Adult mapt Knockout Mouse. [PDF]

open access: yesInt J Mol Sci, 2023
Andrés-Benito P   +10 more
europepmc   +1 more source

Development of a Disease Model for Predicting Postoperative Delirium Using Combined Blood Biomarkers

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Postoperative delirium, a common neurocognitive complication after surgery and anesthesia, requires early detection for potential intervention. Herein, we constructed a multidimensional postoperative delirium risk‐prediction model incorporating multiple demographic parameters and blood biomarkers to enhance prediction accuracy ...
Hengjun Wan   +7 more
wiley   +1 more source

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