Results 171 to 180 of about 415,720 (292)

Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model. [PDF]

Orphanet J Rare Dis
Wang S, Shen M, Pang B, Zhou B, Yuan Y, Lu M, Deng X, Yang M, Liu S, Wang Q, Xue M, Xia Q, Zhang Z.   +12 more
europepmc   +1 more source

Carbon Nanodots Attenuate Lipid Peroxidation in the LDL Receptor Knockout Mouse Brain. [PDF]

Antioxidants (Basel), 2023
Erikson KM, El-Khouri K, Petric R, Tang C, Chen J, Vasquez DEC, Fordahl SC, Jia Z.   +7 more
europepmc   +1 more source

Sequential analysis of kidney stone formation in the Aprt knockout mouse

, 2001
Andrew P. Evan, Sharon B. Bledsoe, Bret A. Connors, Li Deng, Li Liang, Changshun Shao, Naomi S. Fineberg, Marc D. Grynpas, P J Stambrook, Youzhi Shao, Amrik Sahota, Jay A. Tischfield   +11 more
openalex   +1 more source

Mouse knockout solves endocrine puzzle and promotes new pituitary lineage model [PDF]

, 2003
Catherine E. Keegan, Sally A. Camper
openalex   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Ferroptosis Contributes to Retinal Ganglion Cell Loss in GLAST Knockout Mouse Model of Normal Tension Glaucoma. [PDF]

Invest Ophthalmol Vis Sci
Ye H, Feng Y, Xiang W, Lin Z, Li Y, Hu W, Liu K, Tao S, Shu Q, Wang J, Xu F, Xu Y, Wei Y, Huang J.   +13 more
europepmc   +1 more source

Inhibition of Glutamine Metabolism Attenuates Tumor Progression Through Remodeling of the Macrophage Immune Microenvironment

Advanced Biology, EarlyView.
The prodrug strategy used in this study offers new promise for cancer metabolism‐based therapies. JHU083, a prodrug that, when cleaved by protease in the tumor microenvironment, yields the glutamine antagonist DON. JHU083 inhibits tumor growth by targeting glutamine‐addicted cancer cells and suppressing glutamine‐dependent M2 macrophages, leading to a ...
Tianhe Li, Sepehr Akhtarkhavari, Sumeng Qi, Jiawei Fan, Tu‐Yung Chang, Yao‐An Shen, JinMing Yang, Barbara S. Slusher, Ie‐Ming Shih, Stephanie Gaillard, Tian‐Li Wang   +10 more
wiley   +1 more source

Characterization of the Ocular Phenotype in a Col4a3 Knockout Mouse Model of Alport Syndrome. [PDF]

Invest Ophthalmol Vis Sci
Belamkar A, Luo Q, Mahajan N, Abhyankar S, Jones BA, Sodhi RK, Pattabiraman PP, Levi M, Bhatwadekar AD.   +8 more
europepmc   +1 more source

Differential Immune Response to Bioprosthetic Heart Valve Tissues in the α1,3Galactosyltransferase-Knockout Mouse Model. [PDF]

Bioengineering (Basel), 2023
Casós K, Llatjós R, Blasco-Lucas A, Kuguel SG, Sbraga F, Galli C, Padler-Karavani V, Le Tourneau T, Vadori M, Perota A, Roussel JC, Bottio T, Cozzi E, Soulillou JP, Galiñanes M, Máñez R, Costa C.   +16 more
europepmc   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source