Results 171 to 180 of about 406,670 (317)

Roles unveiled for membrane-associated mucins at the ocular surface using a Muc4 knockout mouse model. [PDF]

Sci Rep, 2023
Martinez-Carrasco R, Rachagani S, Batra SK, Argüeso P, Fini ME.   +4 more
europepmc   +1 more source

Molecular pharmacology of prostaglandin E receptor subtypes –structure, signal transduction, and knockout mouse studies–

, 2000
Atsushi Ichikawa, Yukihiko Sugimoto, Masahiko Negishi, Shu Narumiya   +3 more
openalex   +1 more source

Partial rescue of the Dazl knockout mouse by the human DAZL gene [PDF]

, 2002
Tanja Vogel
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Slc35a2 mosaic knockout impacts cortical development, dendritic arborisation, and neuronal firing

Neurobiology of Disease
Mild malformation of cortical development with oligodendroglial hyperplasia in epilepsy (MOGHE) is an important cause of drug-resistant epilepsy. A significant subset of individuals diagnosed with MOGHE display somatic mosaicism for loss-of-function ...
James Spyrou, Khaing Phyu Aung, Hannah Vanyai, Richard J. Leventer, Snezana Maljevic, Paul J. Lockhart, Katherine B. Howell, Christopher A. Reid   +7 more
doaj  

Characterization of an intelectin-1 (Itln1) knockout mouse model. [PDF]

Front Immunol, 2022
Nonnecke EB, Castillo PA, Akahoshi DT, Goley SM, Bevins CL, Lönnerdal B.   +5 more
europepmc   +1 more source

Elevated susceptibility of the p53 knockout mouse esophagus to methyl-N-amylnitrosamine carcinogenesis [PDF]

, 2002
Norimitsu Shirai
openalex   +1 more source

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model. [PDF]

Orphanet J Rare Dis
Wang S, Shen M, Pang B, Zhou B, Yuan Y, Lu M, Deng X, Yang M, Liu S, Wang Q, Xue M, Xia Q, Zhang Z.   +12 more
europepmc   +1 more source

Gene augmentation therapy attenuates retinal degeneration in a knockout mouse model of Fam161a retinitis pigmentosa. [PDF]

Mol Ther, 2023
Matsevich C, Gopalakrishnan P, Chang N, Obolensky A, Beryozkin A, Salameh M, Kostic C, Sharon D, Arsenijevic Y, Banin E.   +9 more
europepmc   +1 more source