Results 221 to 230 of about 1,863,148 (392)

Impaired hippocampal representation of place in the Fmr1-knockout mouse model of fragile X syndrome [PDF]

, 2018
Tara Arbab, Cyriel M. A. Pennartz, Francesco P. Battaglia   +2 more
openalex   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Generation of a new Slc20a2 knockout mouse line as in vivo model for primary brain calcification. [PDF]

Mol Brain
Kurita H, Kitaura H, Nishii K, Masaka T, Ohuchi K, Inden M, Kakita A, Osawa M, Hozumi I.   +8 more
europepmc   +1 more source

Generation and analysis of mouse embryonic stem cells with knockout of the Mcph1 (microcephalin) gene

Anastasia Yunusova, A. V. Smirnov, Т. А. Шнайдер, I. E. Pristyazhnuk, S. Y. Korableva, Nariman Battulin   +5 more
openalex   +2 more sources

Voluntary exercise prevents the obese and diabetic metabolic syndrome of the melanocortin‐4 receptor knockout mouse

, 2008
Carrie Haskell‐Luevano, Jay W. Schaub, Amy Andreasen, Kim R. Haskell, Marcus C. Moore, Lorraine M. Koerper, François Rouzaud, Henry V. Baker, William J. Millard, Glenn Walter, Sally A. Litherland, Zhimin Xiang   +11 more
openalex   +1 more source

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons, Todd Levine, Charles H. Adler, Bailey Bellaire, Ningshan Wang, Pinky Agarwal, Georgina M. Aldridge, Alexandru Barboi, Daniel Claassen, Virgilio G. H. Evidente, Douglas Galasko, Alejandra Gonzalez‐Duarte, Ramon Gil, Mark Gudesblatt, Stuart H. Isaacson, Horacio Kaufmann, Pravin Khemani, Rajeev Kumar, Guillaume Lamotte, Andy J. Liu, Nikolaus R. McFarland, Mitchell G. Miglis, Adam Reynolds, Gregory A. Sahagian, Marie‐Helene Saint‐Hilaire, Julie B. Schwartzbard, Wolfgang Singer, Michael J. Soileau, Steven Vernino, Patricio Millar Vernetti, Oleg Yerstein, Roy Freeman   +31 more
wiley   +1 more source

Exploring the nucleus accumbens circuit and oxytocin therapy in a Sapap3 knockout mouse model of trichotillomania. [PDF]

Sci Rep
Wang Y, Yu J, Ma R, Chen Y, Lu S, Fang J.   +5 more
europepmc   +1 more source

Protease activity of legumain is inhibited by an increase of cystatin E/M in the DJ-1-knockout mouse spleen, cerebrum and heart

, 2017
T. Yamane, Miyuki Kozuka, Yoshio Yamamoto, Yoshihisa Nakano, Takenori Nakagaki, Iwao Ohkubo, Hiroyoshi Ariga   +6 more
openalex   +1 more source

Sexual Dimorphism in the Selenocysteine Lyase Knockout Mouse [PDF]

, 2018
Ashley N. Ogawa-Wong, Ann C. Hashimoto, Herena Y. Ha, Matthew W. Pitts, Lucia A. Seale, Marla J. Berry   +5 more
openalex   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source