Results 261 to 270 of about 1,863,148 (392)

Rescue of cone function in cone-only Nphp5 knockout mouse model with Leber congenital amaurosis phenotype.

, 2018
Christin Hanke‐Gogokhia, Vince A. Chiodo, William W. Hauswirth, Jeanne M. Frederick, Wolfgang Baehr   +4 more
openalex   +1 more source

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

Nature, 2017
Yang Shi, Kaoru Yamada, S. A. Liddelow, Scott t. Smith, Lingzhi Zhao, Wenjie Luo, Richard M. Tsai, S. Spina, L. Grinberg, J. Rojas, G. Gallardo, Kairuo Wang, Joseph Roh, Grace O Robinson, M. B. Finn, Hong Jiang, P. Sullivan, Caroline Baufeld, M. Wood, C. Sutphen, Lena McCue, C. Xiong, Jorge L. Del-Aguila, J. Morris, C. Cruchaga, A. Fagan, B. Miller, A. Boxer, W. Seeley, O. Butovsky, B. Barres, S. Paul, D. Holtzman   +32 more
semanticscholar   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Impaired cognitive function and decreased monoamine neurotransmitters in the DNAJC12 gene knockout mouse model. [PDF]

Orphanet J Rare Dis
Wang S, Shen M, Pang B, Zhou B, Yuan Y, Lu M, Deng X, Yang M, Liu S, Wang Q, Xue M, Xia Q, Zhang Z.   +12 more
europepmc   +1 more source

Generation and Validation of a Mouse Line with a Floxed SRC-3/AIB1 Allele for Conditional Knockout

, 2008
L. Liu
openalex   +1 more source

Additional file 3 of Plasminogen activator inhibitor-2 (PAI-2) overexpression supports bladder cancer development in PAI-1 knockout mice in N-butyl-N- (4-hydroxybutyl)-nitrosamine- induced bladder cancer mouse model

, 2020
Hideki Furuya, Kazukuni Hayashi, Yoshiko Shimizu, Nari Kim, Yutaro Tsukikawa, Runpu Chen, Yijun Sun, Owen Chan, Ian Pagano, Rafael Peres, Kanani Hokutan, Fumie Igari, Keith Syson Chan, Charles J. Rosser   +13 more
openalex   +1 more source

Dynamic Precipitation during High‐Pressure Torsion of a Magnesium–Manganese Alloy

Advanced Engineering Materials, EarlyView.
An ultrafine‐grained alloy is produced by high‐pressure torsion of solutionized Mg–1.35 wt% Mn. Precipitation of nanometer‐scale Mn particles during deformation provides pinning sites. This prevents the formation of a bimodal grain structure and results in a finer grain size than for pure Mg.
Julian M. Rosalie, Anton Hohenwarter
wiley   +1 more source

Ferroptosis Contributes to Retinal Ganglion Cell Loss in GLAST Knockout Mouse Model of Normal Tension Glaucoma. [PDF]

Invest Ophthalmol Vis Sci
Ye H, Feng Y, Xiang W, Lin Z, Li Y, Hu W, Liu K, Tao S, Shu Q, Wang J, Xu F, Xu Y, Wei Y, Huang J.   +13 more
europepmc   +1 more source

Quantum Emitters in Hexagonal Boron Nitride: Principles, Engineering and Applications

Advanced Functional Materials, EarlyView.
Quantum emitters in hexagonal boron nitride have emerged as a promising candidate for quantum information science. This review examines the fundamentals of these quantum emitters, including their level structures, defect engineering, and their possible chemical structures.
Thi Ngoc Anh Mai, Md Shakhawath Hossain, Nhat Minh Nguyen, Yongliang Chen, Chaohao Chen, Xiaoxue Xu, Quang Thang Trinh, Toan Dinh, Toan Trong Tran   +8 more
wiley   +1 more source

Characterization of the Ocular Phenotype in a Col4a3 Knockout Mouse Model of Alport Syndrome. [PDF]

Invest Ophthalmol Vis Sci
Belamkar A, Luo Q, Mahajan N, Abhyankar S, Jones BA, Sodhi RK, Pattabiraman PP, Levi M, Bhatwadekar AD.   +8 more
europepmc   +1 more source