Results 311 to 320 of about 1,863,148 (392)

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Desipramine reverses remote memory deficits by activating calmodulin-CaMKII pathway in a UTX knockout mouse model of Kabuki syndrome. [PDF]

Gen Psychiatr
Chen L, Li Y, Liu M, Lan Z, Zhang X, Yang X, Zhao Q, Wang S, Xu L, Zhou Y, Kuang Y, Suzuki T, Tabuchi K, Takahashi E, Zhou M, Chen CD, Xu T, Li W.   +17 more
europepmc   +1 more source

Colloidal Crack Sintering Lithography for Light‐Induced Patterning of Particle Assemblies

Advanced Functional Materials, EarlyView.
Colloidal crack sintering lithography (CCSL) is a microfabrication technique that uses light‐induced photothermal heating to trigger sintering and controlled cracking in polymer colloidal assemblies. Local structural changes generate microchannels and patterns, enabling direct writing of diverse topographic motifs.
Marius Schoettle, Ariane V. Mader, Willem L. Noorduin   +2 more
wiley   +1 more source

Conditional knockout mouse model reveals a critical role of peroxiredoxin 1 in oral leukoplakia carcinogenesis. [PDF]

Heliyon
Li L, Li J, Lu Y, Li W, Yang J, Wang M, Miao C, Tian Z, Zhang M, Tang X.   +9 more
europepmc   +1 more source

Deletion of HIF-1α partially rescues the abnormal hyaloid vascular system in Cited2 conditional knockout mouse eyes.

, 2012
Tai Qin Huang, Yiwei Wang, Quteba Ebrahem, Yu Chen, Cindy Cheng, Yong Qiu Doughman, Michiko Watanabe, Sally L. Dunwoodie, Y C Yang   +8 more
openalex   +1 more source

Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy

Advanced Functional Materials, EarlyView.
FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao, Yejing Zhu, Hengchao Yu, Jun Zhu, Bo Wang, Yu Qiao, Zhimin Tian, Junlong Zhao, Lei Liu   +8 more
wiley   +1 more source

Quantifiable and reproducible phenotypic assessment of a constitutive knockout mouse model for congenital nephrotic syndrome of the Finnish type. [PDF]

Sci Rep
Lemberg K, Mertens ND, Yousef K, Schneider R, Merz LM, Mansour B, Salmanullah D, Kolvenbach CM, Saida K, Yu S, Hölzel S, Steinsapir A, Goncalves KA, Nicolas Frank C, Franken GAC, Shril S, Buerger F, Hildebrandt F.   +17 more
europepmc   +1 more source

Mesoporous Carbon Thin Films with Large Mesopores as Model Material for Electrochemical Applications

Advanced Functional Materials, EarlyView.
Mesoporous carbon thin films possessing 70 nm mesopores are prepared on titanium substrates by soft templating of resol resins with a self‐synthesized poly(ethylene oxide)‐block‐poly(hexyl acrylate) block copolymer. A strategy to avoid corrosion of the metal substrate is presented, and the films are extensively characterized in terms of morphology ...
Lysander Q. Wagner, Joshua Schober, Pascal Dippell, Chantal Glatthaar, Smail Mekhilef, David Schäfer, Hannes Hergert, Marcus Rohnke, Matthias T. Elm, Bernd M. Smarsly   +9 more
wiley   +1 more source

Defining the <i>In Vivo</i> Role of mTORC1 in Thyrocytes by Studying the TSC2 Conditional Knockout Mouse Model. [PDF]

Thyroid
Rossetti CL, Alves BL, Peçanha FLM, Franco AT, Nosé V, Carneiro EM, Lew J, Bernal-Mizrachi E, Werneck-de-Castro JP.   +8 more
europepmc   +1 more source