Results 71 to 80 of about 556,186 (309)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Krishnamurti and Transforming the World’s Mind [PDF]
Journal of Unschooling and Alternative LearningFor this article, I have adapted a talk I gave for an online conference centering around Jiddu Krishnamurti’s scholarship to address the theme of “a world in crisis.” I share a narrative of my experience discovering Krishnamurti’s work by way of ...
Kathryn Jefferies
doaj
Communal Knowing in Nursing: A Novel Pattern of Knowing From the African Philosophical Lens
African philosophical thoughts suggest that personhood is founded on and can be understood as emerging from the community. Thus, the community is essential to understanding personhood.
Bayuo, Jonathan
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Negotiating knowledges and expertise in refugee resettlement organizations
Cogent Social Sciences, 2016 Interviews with both refugees and organizational staff in two nonprofit refugee resettlement organizations in the United States reveal the ways in which knowledge(s) and expertise are crafted, threatened, and understood in refugee organizations.
Sarah Steimel
doaj +1 more source
Knowing One's Own Consciousness: The Epistemic Ontology of Consciousness and Its Implication for the Explanatory Gap Argument(s) [PDF]
Pizhūhish/hā-yi Falsafī- KalāmīIt is usually, and without much disagreement, regarded that 'knowing one's own consciousness' is strikingly and fundamentally different from 'knowing other things.' The peculiar way in which conscious subjects introspectively know their own consciousness
Biplab Karak
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
An auto/biographical, cooperative study of ourrelationships to knowing [PDF]
, 2016 In this thesis, I explore the relationship between knowing and self-construction among education professionals. The work addresses questions about our relationship with different ways of knowing; and within what I term a psychosocial framework, how the ...
Del Negro, G.
core