Results 61 to 70 of about 21,842,130 (342)

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Determinants of quality of life amongst hearing impaired patients in a rural district of South Africa: a cross-sectional study

Discover Social Science and Health
Background Hearing loss is one of the leading causes of disability worldwide, affecting individuals across all age groups. Its impact extends beyond auditory function, influencing overall health-related quality of life (HRQoL) and presenting significant ...
Lwazi Knowledge Mnguni, Ozayr Mahomed
doaj   +1 more source

Using a distribution-based approach and systematic review methods to derive minimum clinically important differences

BMC Medical Research Methodology, 2021
Background Clinical interpretation of changes measured on a scale is dependent on knowing the minimum clinically important difference (MCID) for that scale: the threshold above which clinicians, patients, and researchers perceive an outcome difference ...
Jennifer A. Watt, Areti Angeliki Veroniki, Andrea C. Tricco, Sharon E. Straus   +3 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Comparing Two Deep-Learning Models in Discrete Choice Analysis of Customers’ Mobile Plan Preferences

Applied Sciences
A discrete choice experiment (DCE) was used to investigate students’ preferences for mobile phone plans at a South African university. Upon obtaining the data, this study compares the predictive performance of two machine-learning models for discrete ...
Chidimma Oliobi, Knowledge Chinhamu, Temesgen Zewotir   +2 more
doaj   +1 more source

Inexact Knowledge

Mind, 1992
Most of our knowledge is inexact, and known by us to be so. An example of such known inexactness will be described in some detail. The description seems to entail a contradiction. However, the paradoxical reasoning rests on an assumption. It will be suggested that the description is correct and this assumption false.
openaire   +3 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Value at Risk long memory volatility models with heavy-tailed distributions for cryptocurrencies

Frontiers in Applied Mathematics and Statistics
This paper investigates the volatility dynamics and underlying long memory features of four major cryptocurrencies—Bitcoin, Ethereum, Litecoin, and Ripple—which were selected due to their high liquidity, large trading volumes, and historical significance
Stephanie Danielle Subramoney, Knowledge Chinhamu, Retius Chifurira   +2 more
doaj   +1 more source

Impact of shortened length of stay for delivery on the required bed capacity in maternity services: results from forecast analysis on administrative data

BMC Health Services Research, 2019
Background We examine the implications of reducing the average length of stay (ALOS) for a delivery on the required capacity in terms of service volume and maternity beds in Belgium, using administrative data covering all inpatient stays in Belgian ...
Mélanie Lefèvre, Koen Van den Heede, Cécile Camberlin, Nicolas Bouckaert, Claire Beguin, Carl Devos, Carine Van de Voorde   +6 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source