Results 61 to 70 of about 21,998,049 (389)

Toward principles for the design of ontologies used for knowledge sharing?

open access: yesInt. J. Hum. Comput. Stud., 1995
Recent work in Artificial Intelligence is exploring the use of formal ontologies as a way of specifying content-specific agreements for the sharing and reuse of knowledge among software entities.
T. Gruber
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Comparing Two Deep-Learning Models in Discrete Choice Analysis of Customers’ Mobile Plan Preferences

open access: yesApplied Sciences
A discrete choice experiment (DCE) was used to investigate students’ preferences for mobile phone plans at a South African university. Upon obtaining the data, this study compares the predictive performance of two machine-learning models for discrete ...
Chidimma Oliobi   +2 more
doaj   +1 more source

Using a distribution-based approach and systematic review methods to derive minimum clinically important differences

open access: yesBMC Medical Research Methodology, 2021
Background Clinical interpretation of changes measured on a scale is dependent on knowing the minimum clinically important difference (MCID) for that scale: the threshold above which clinicians, patients, and researchers perceive an outcome difference ...
Jennifer A. Watt   +3 more
doaj   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Representing knowledge about knowledge and mutual knowledge [PDF]

open access: yesProceedings of the 22nd annual meeting on Association for Computational Linguistics -, 1984
In order to represent speech acts, in a multi-agent context, we choose a knowledge representation based on the modal logic of knowledge KT4 which is defined by Sato. Such a formalism allows us to reason about knowledge and represent knowledge about knowledge, the notions of truth value and of definite reference.
openaire   +1 more source

Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Extracellular vesicles (EVs) mediate intercellular communication in tumor immune microenvironments. However, their role in B‐cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis.
Daniel Bachurski, Michael Hallek
wiley   +1 more source

Impact of shortened length of stay for delivery on the required bed capacity in maternity services: results from forecast analysis on administrative data

open access: yesBMC Health Services Research, 2019
Background We examine the implications of reducing the average length of stay (ALOS) for a delivery on the required capacity in terms of service volume and maternity beds in Belgium, using administrative data covering all inpatient stays in Belgian ...
Mélanie Lefèvre   +6 more
doaj   +1 more source

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