Results 91 to 100 of about 7,833,055 (290)

A Knowledge Argument for Time [PDF]

open access: yes
On being released from her black-and-white room into a colorful world it would seem Mary learns something new (the Knowledge Argument). On being released from his B-theory room into an A-theory world it would seem Mark learns something new (the Temporal
Merriam, Paul
core   +2 more sources

An Argument for Expanding Research on Quantitative Pedagogical Content Knowledge

open access: yesNumeracy
Pedagogical content knowledge (PCK) traditionally has been used in research concerning prospective and practicing classroom teachers. This essay argues that PCK is also relevant to other professions including those advancing quantitative reasoning (QR ...
Randall Groth
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Combinatorial Axiology and the Problem of Evil

open access: yesReligions
In this article, I argue that the probabilistic argument from evil rests on an assumption that weakens its conclusion. The argument presupposes epistemic conditions that we are not in a position to meet.
Elliott R. Crozat
doaj   +1 more source

A glance to the epistemology based on the knowledge of the God in Shikh-e- Mufid and Allameh Tabatabai's thought [PDF]

open access: yesحکمت و فلسفه, 2016
According to Shikh-e- Mufid, knowledge has propositional and assertoric form obtained either from sense and observation; in this case, knowledge is self-evident or it achieved from rational argument and repeated news, then, it is acquisitive knowledge or
morteza erfani   +2 more
doaj  

The Argument from Underconsideration and Relative Realism [PDF]

open access: yes, 2013
In this paper, through a critical examination of Wray’s version of the argument from underconsideration against scientific realism, I articulate a modest version of scientific realism.
Mizrahi, Moti
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Home - About - Disclaimer - Privacy