Results 51 to 60 of about 8,364,979 (244)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
A study on Carl Bereiter`s conceptualization of education [PDF]
فصلنامه نوآوریهای آموزشی, 2011 The purpose of this study was to investigate Carl Bereiter`s conceptualization of education. In fact, the main aim was to critique his view of education and study its applicability in action.
Mahmood Talkhabi, Kamal Kharrazi
doaj
Innovation Entanglement at Three South African Tech Hubs
The African Journal of Information and Communication, 2020 This study explores innovation modalities at three South African tech hubs: Bandwidth Barn Khayelitsha and Workshop 17 in Cape Town, and the Tshimologong Digital Innovation Precinct in Johannesburg. The study finds that tech start-ups’ ability to scale
Lucienne Abrahams
doaj +1 more source
, 2006 Knowledge management (KM) is a newly emerging approach aimed at addressing today’s business challenges to increase efficiency and efficacy of core business processes, while simultaneously incorporating continuous innovation. The need for knowledge management is based on a paradigm shift in the business environment where knowledge is now considered to ...
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Integrative Determinants of Innovation Performance: The Role of Learning Organization and Knowledge Creation [PDF]
Pakistan Journal of Commerce and Social Sciences, 2017 This study looks into the mediating effects of knowledge creation in the relationship between learning organization (LO) practices and innovation performance.
Syed Harris Laeeque (Corresponding author)
doaj
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Practices in knowledge management of the agricultural family business
Ra Ximhai, 2020 The present study has the objective of describing from a qualitative perspective, the current situation in the knowledge management of the agricultural family business belonging to the state of Sinaloa.
Diana Alejandra León Torres +1 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Airway, 2020 The aim of this article is to ignite the minds of readers and empower them to create new knowledge in relation to 'emergency difficult airway access'.
Arumugam Ramesh
doaj +1 more source