Results 61 to 70 of about 9,383,085 (340)

Innovation Entanglement at Three South African Tech Hubs

open access: yesThe African Journal of Information and Communication, 2020
This study explores innovation modalities at three South African tech hubs: Bandwidth Barn Khayelitsha and Workshop 17 in Cape Town, and the Tshimologong Digital Innovation Precinct in Johannesburg. The study finds that tech start-ups’ ability to scale
Lucienne Abrahams
doaj   +1 more source

Knowledge Creation [PDF]

open access: yes, 2006
Knowledge management (KM) is a newly emerging approach aimed at addressing today’s business challenges to increase efficiency and efficacy of core business processes, while simultaneously incorporating continuous innovation. The need for knowledge management is based on a paradigm shift in the business environment where knowledge is now considered to ...
openaire   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The Integrative Determinants of Innovation Performance: The Role of Learning Organization and Knowledge Creation [PDF]

open access: yesPakistan Journal of Commerce and Social Sciences, 2017
This study looks into the mediating effects of knowledge creation in the relationship between learning organization (LO) practices and innovation performance.
Syed Harris Laeeque (Corresponding author)
doaj  

Practices in knowledge management of the agricultural family business

open access: yesRa Ximhai, 2020
The present study has the objective of describing from a qualitative perspective, the current situation in the knowledge management of the agricultural family business belonging to the state of Sinaloa.
Diana Alejandra León Torres   +1 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion

open access: yes
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana   +8 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Knowledge creation in knowledge-intensive small and medium sized enterprises

open access: yesInternational Journal of Knowledge-Based Development, 2019
The paper presents insights into the knowledge creation process in three Icelandic knowledge-intensive small and medium-sized enterprises (SMEs). Data were obtained through a case study methodology.
Elsa Grimsdottir   +2 more
semanticscholar   +1 more source

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