Results 71 to 80 of about 9,383,085 (340)

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Supporting the creation and installation of regional social innovations with knowledge engineering system

open access: yesMarketing i Menedžment Innovacij, 2017
The aim of the article. The aim of the article is identification of essence and features of application of social innovation in the current economic conditions of the Republic of Hungary.
G. Kocziszky, M. Veresné Somosi
doaj   +1 more source

Non-discursive knowledge and the construction of identity. Potters, potting and performance at the bronze age tell of Százhalombatta, Hungary [PDF]

open access: yes, 2009
This article explores the relationship between the making of things and the making of people at the Bronze Age tell at Százhalombatta, Hungary. Focusing on potters and potting, we explore how the performance of non-discursive knowledge was critical to ...
Budden, Sandy, Sofaer, Joanna
core   +1 more source

Knowledge Management, Knowledge Creation, and Open Innovation in Icelandic SMEs

open access: yesSAGE Open, 2018
The aim of this article is to present findings on knowledge management (KM) and knowledge creation, as well as open innovation in small and medium-sized enterprises (SMEs) in Iceland. Two SME company case studies are presented in the form of a case study
Elsa Grimsdottir, I. Edvardsson
semanticscholar   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Restoring Trust: The Role of HR in Corporate Governance [PDF]

open access: yes, 2003
Theories of knowledge-based competition focus on internal resources as the source of value creation. The HR architecture (Lepak & Snell, 1999) brought human resource management directly into this forum by developing a model of human capital allocation ...
Wright, Patrick M.
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

From knowledge dependence to knowledge creation: Industrial growth and the technological advance of the Japanese electronics industry [PDF]

open access: yes, 2001
The thrust of the argument put forward in this paper is that the postwar technological advance of the Japanese electronics industry was in essence a product not a primary cause of industrial growth.
Harvey, Charles   +2 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Exploring Knowledge Creation Processes as a Source of Organizational Learning: A Longitudinal Case Study of a Public Innovation Project

open access: yes, 2017
The purpose of the study is to reestablish the link between theories of organizational learning and knowledge creation – theories that in research, have been pursued as independent themes for almost two decades.
J. Brix
semanticscholar   +1 more source

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