Results 101 to 110 of about 1,911,756 (319)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

A Method for Extracting Fine-Grained Knowledge of the Wheat Production Chain

open access: yesAgronomy
The knowledge within wheat production chain data has multiple levels and complex semantic relationships, making it difficult to extract knowledge from them.
Jing Lu   +5 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

In Search of L-Fuzzy Contexts Adaptable to Variable Information: A Tool for Time-Varying Data Analysis

open access: yesAxioms
This paper sheds light on the study of a new structure, called L-fuzzy hypercontext, which provides an extension of the range of applications of fuzzy concept analysis.
Cristina Alcalde, Ana Burusco
doaj   +1 more source

Corpus-Driven Knowledge Acquisition for Discourse Analysis

open access: yes, 1994
The availability of large on-line text corpora provides a natural and promising bridge between the worlds of natural language processing (NLP) and machine learning (ML).
Lehnert, Wendy, Soderland, Stephen
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Feedback Collection and Nearest-Neighbor Profiling for Recommendation Systems in Healthcare Scenarios

open access: yesTechnologies
The rise in the dimension and complexity of information generated in the clinical field has motivated research on the automation of tasks in personalized healthcare.
João António   +2 more
doaj   +1 more source

Automatic transparency evaluation for open knowledge extraction systems. [PDF]

open access: yesJ Biomed Semantics, 2023
Basereh M, Caputo A, Brennan R.
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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