Results 61 to 70 of about 1,918,144 (294)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Gender-Based Analysis of User Reactions to Facebook Posts

Big Data Mining and Analytics
Online Social Networks (OSNs) are based on the sharing of different types of information and on various interactions (comments, reactions, and sharing). One of these important actions is the emotional reaction to the content.
Yassine El Moudene, Jaafar Idrais, Rida El Abassi, Abderrahim Sabour   +3 more
doaj   +1 more source

Web based knowledge extraction and consolidation for automatic ontology instantiation [PDF]

, 2003
The Web is probably the largest and richest information repository available today. Search engines are the common access routes to this valuable source.
Alani, Harith, Hall, Wendy, Kim, Sanghee, Lewis, Paul H., Millard, David E., Shadbolt, Nigel, Weal, Mark J.   +6 more
core   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Preliminary Study on the Knowledge Graph Construction of Chinese Ancient History and Culture

Information, 2020
The domestic population has paid increasing attention to ancient Chinese history and culture with the continuous improvement of people’s living standards, the rapid economic growth, and the rapid advancement of information science and technology. The use
Shuang Liu, Hui Yang, Jiayi Li, Simon Kolmanič   +3 more
doaj   +1 more source

AQUA: an ontology driven question answering system [PDF]

, 2003
This paper describes AQUA our question answering over the Web. AQUA was designed to work over heterogeneous sources. This means that AQUA is equipped to work as closed domain and in addition to open-domain question answering.
Domingue, John, Motta, Enrico, Vargas-Vera, Maria   +2 more
core  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Learning to Navigate in Mixed Human–Robot Crowds via an Attention-Driven Deep Reinforcement Learning Framework

Machine Learning and Knowledge Extraction
The rapid growth of technology has introduced robots into daily life, necessitating navigation frameworks that enable safe, human-friendly movement while accounting for social aspects.
Ibrahim K. Kabir, Muhammad F. Mysorewala, Yahya I. Osais, Ali Nasir   +3 more
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source