Results 51 to 60 of about 351,050 (219)

A Knowledge Graph Completion Method Based on Fusing Association Information

open access: yesIEEE Access, 2022
Knowledge graph is a carrier of knowledge. The knowledge graph completion task is to predict the links between entities to make the knowledge graph more complete.
Yuhao Wang, Erping Zhao, Wei Wang
doaj   +1 more source

Automatic Inference of Graph Transformation Rules Using the Cyclic Nature of Chemical Reactions

open access: yes, 2016
Graph transformation systems have the potential to be realistic models of chemistry, provided a comprehensive collection of reaction rules can be extracted from the body of chemical knowledge. A first key step for rule learning is the computation of atom-
Flamm, Christoph   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Does William Shakespeare REALLY Write Hamlet? Knowledge Representation Learning with Confidence

open access: yes, 2018
Knowledge graphs (KGs), which could provide essential relational information between entities, have been widely utilized in various knowledge-driven applications.
Lin, Fen   +3 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Hamming Distance Encoding Multihop Relation Knowledge Graph Completion

open access: yesIEEE Access, 2020
Knowledge graphs (KGs) play an important role in many real-world applications like information retrieval, question answering, relation extraction, etc. To reveal implicit knowledge from a knowledge graph (KG), viz.
Panfeng Chen   +4 more
doaj   +1 more source

On Minimizing the Completion Times of Long Flows over Inter-Datacenter WAN

open access: yes, 2018
Long flows contribute huge volumes of traffic over inter-datacenter WAN. The Flow Completion Time (FCT) is a vital network performance metric that affects the running time of distributed applications and the users' quality of experience.
Noormohammadpour, Mohammad   +2 more
core   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Federated Learning FedLTailor: A Dynamic Weight Adjustment and Personalized Fusion Approach

open access: yesIEEE Access
In this study, we primarily address the issue of uneven quality of client embeddings in existing federated learning frameworks for knowledge graph completion.
Hong Zheng, Shanqin Li
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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