Results 71 to 80 of about 17,415,345 (386)

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Krishikosh: A digital repository to disseminate agricultural knowledge

The Indian Journal of Agricultural Sciences, 2018
Krishikosh is a versatile open access digital repository catering to the needs of Indian National Agricultural Research and Education System (NARES) and has architecture of centralized hosting of content but decentralized management.
RAKHEE SHARMA, AMRENDER KUMAR, P S PANDEY, HIMANSHU HIMANSHU, MANSI GUPTA, SANJIV KAPUR, ASHISH SHARMA, A K JAIN   +7 more
doaj   +1 more source

Perancangan Knowledge Management System Berbasis Wiki untuk Pengelolaan Pengalaman Mahasiswa Praktik [PDF]

, 2016
Clinic practicum program of Faculty of Health, of Satya Wacana Christian University,  is one of the program with the purpose to carry on students\u27 clinic  learning which is integrated the theory and practical work at hospital.
Bobode, M. (Mahersy), Papilaya, F. S. (Frederik), Wenas, M. B. (Michael)   +2 more
core  

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Resilience in the Vaccine Supply Chain: Learning from the COVID-19 Pandemic

Vaccines
Background: The COVID-19 pandemic revealed vaccine supply chain (VSC) weaknesses and enabled post-pandemic analysis highlighting the growing importance of supply chain resilience.
Megan Hay, Anika Teichert, Sarah Kilz, Agnes Vosen   +3 more
doaj   +1 more source

Knowledge Dissemination based on Social Networks: A Systematic Review [PDF]

کتابداری و اطلاع‌رسانی
Objective: Knowledge is an asset that increases when others share it, and its sharing and dissemination leads to synergy and growth of individual and collective knowledge.
Leila Jabbari, Mohammad Hasanzadeh, Fatemeh Zandian, Atefeh Sharif   +3 more
doaj   +1 more source

Building knowledge-based economies: research projects in knowledge management and knowledge transfer [PDF]

, 2000
Small and medium-sized enterprises (SMEs) are viewed as the growth engines of the new knowledgebased economy. This new economic growth model differs from the old in significant ways, many of which are related to the knowledge base that will be required
Gibson, Virginia R.
core  

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

Molecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh, Nikola Tom, Anna Schrøder Lassen, Helene Brasch Lind Petersen, Ulrik Kristoffer Stoltze, Karin Wadt, Kjeld Schmiegelow, Matteo Tiberti, Elena Papaleo   +8 more
wiley   +1 more source

The Effect of Book Therapy on Mental Health of Prisoners (Case Study: Defamation of Women in Shahr-e-Rey, Iran)

مدیریت اطلاعات سلامت, 2019
Introduction: Book therapy is an effective and practical process that can prevent or reduce a range of mental health problems. Prisoners are among the most in need of attention in terms of mental health.
Fatemeh Zandian, Fatemeh Valipour, Mohamad Hasanzadeh   +2 more
doaj   +1 more source