Results 81 to 90 of about 5,403,631 (298)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Detection and Removal of Noise in Images Based on Amount of Knowledge Associated with Intuitionistic Fuzzy Sets [PDF]

open access: yesJisuanji kexue yu tansuo
In response to the shortcomings of existing image noise detection algorithms that rely on the flawed intuitionistic fuzzy entropy (IFE) theory, a method of image noise detection and removal based on intuitionistic fuzzy amount of knowledge (IFAK) is ...
GUO Kaihong, ZHOU Yongzhi, WU Zheng, ZHANG Lei
doaj   +1 more source

Demand-Weighted Completeness Prediction for a Knowledge Base

open access: yes, 2018
In this paper we introduce the notion of Demand-Weighted Completeness, allowing estimation of the completeness of a knowledge base with respect to how it is used.
Gurdasani, Amit   +3 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Responses of User to New Media Application in Mpu Tantular Museum, East java [PDF]

open access: yes, 2011
The purpose of this paper is to measure user’s responses of the New Media application. An application, called CD Interaktif, is installed to the Museum Mpu Tantular of East Java.
Luik, Jandy E, Priyowidodo, Gatut
core  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Knowledge, networks of cities and growth in regional urban systems: theory, measurement and policy implications [PDF]

open access: yes
The objective of this paper is to measure the impact of different kinds of knowledge and external economies on the urban growth in an intraregional network of cities. The paper is divided in five sections.
Joan Trullén, Rafael Boix
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

HOW TO MEASURE THE ECONOMY BASED OF KNOWLEDGE : A SHORT REVIEW [PDF]

open access: yesManagement Intercultural, 2013
In this work was outlined essence of the knowledge economy and characterized its basic components. The objectives in this article were based on synthesis the role of the knowledge economy. These studies have a high degree of novelty and complexity of the
Aurelia TURCAN
doaj  

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