A template-based knowledge reuse method for generating multitype 3D railway scenes
International Journal of Digital Earth, 2018 Constructing 3D railway scenes helps improve the railway information construction ability and the comprehensive railway management level. However, the existing modeling methods have disadvantages such as low flexibility in scene configuration, weak ...
Heng Zhang +7 more
doaj +1 more source
A domain-knowledge modeling of hospital-acquired infection risk in Healthcare personnel from retrospective observational data: A case study for COVID-19. [PDF]
PLoS One, 2022 Huynh PK +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Semantic Integration of Heterogeneous Data Sources Using Ontology-Based Domain Knowledge Modeling for Early Detection of COVID-19. [PDF]
SN Comput Sci, 2022 Thirumahal R +2 more
europepmc +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Pattern of Substance Use and Related Factors in Male Prisoners [PDF]
Addiction and Health, 2016 Background: Prisoner’s addiction is one of the major problems in many countries which imposes very high medical costs and social harm to communities. This study investigated the pattern of substance use and related factors in male prisoners in one of the
Ali Khalooei +3 more
doaj
Probabilistic domain-knowledge modeling of disorder pathogenesis for dynamics forecasting of acute onset. [PDF]
Artif Intell Med, 2021 Huynh PK, Setty A, Phan H, Le TQ.
europepmc +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Clinical Decision Support System Based on Hybrid Knowledge Modeling: A Case Study of Chronic Kidney Disease-Mineral and Bone Disorder Treatment. [PDF]
Int J Environ Res Public Health, 2021 Ali SI +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source