Results 101 to 110 of about 2,443,581 (299)
Cyberbullying on social networks has emerged as a pressing global issue, yet research in low-resource languages such as Bengali remains underdeveloped due to the scarcity of high-quality datasets, linguistic resources, and targeted methodologies.
Md. Nesarul Hoque +6 more
doaj +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The Hierarchical Approach to Modeling Knowledge and Common Knowledge [PDF]
One approach to representing knowledge or belief of agents, used by economists and computer scientists, involves an infinite hierarchy of beliefs. Such a hierarchy consists of an agent's beliefs about the state of the world, his beliefs about other ...
John Geanakoplos +3 more
core
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
GAMETH A Process Modeling Approach to Identify and Locate Crucial Knowledge. [PDF]
In a knowledge management initiative, one of the main issues is to identify and locate which knowledge to capitalize on. To deal with this issue, a General Analysis Methodology so called GAMETH® has been developed.
Grundstein, Michel +1 more
core
Knowledge Grid Based Knowledge Supply Model
This paper is mainly concerned with a knowledge supply model in the environment of knowledge grid to realize the knowledge sharing globally. By integrating members, roles, and tasks in a workflow, three sorts of knowledge demands are gained. Based on knowledge demand information, a knowledge supply model is proposed for the purpose of delivering the ...
Lu Zhen, Zuhua Jiang
openaire +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
PARAMETRIC IDENTIFICATION IN KNOWLEDGE ESTIMATION MODELING
The assessment of quality of training is the cornerstone of processes of stimulation of educational activity of the student, quality management of training, management of training as process of development of new knowledge etc.
Irina N. Maslyakova +1 more
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source

