Results 101 to 110 of about 2,443,581 (299)

Advancing cyberbullying detection in low-resource languages: a transformer- stacking framework for Bengali

open access: yesFrontiers in Artificial Intelligence
Cyberbullying on social networks has emerged as a pressing global issue, yet research in low-resource languages such as Bengali remains underdeveloped due to the scarcity of high-quality datasets, linguistic resources, and targeted methodologies.
Md. Nesarul Hoque   +6 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

The Hierarchical Approach to Modeling Knowledge and Common Knowledge [PDF]

open access: yes
One approach to representing knowledge or belief of agents, used by economists and computer scientists, involves an infinite hierarchy of beliefs. Such a hierarchy consists of an agent's beliefs about the state of the world, his beliefs about other ...
John Geanakoplos   +3 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

GAMETH A Process Modeling Approach to Identify and Locate Crucial Knowledge. [PDF]

open access: yes
In a knowledge management initiative, one of the main issues is to identify and locate which knowledge to capitalize on. To deal with this issue, a General Analysis Methodology so called GAMETH® has been developed.
Grundstein, Michel   +1 more
core  

Knowledge Grid Based Knowledge Supply Model

open access: yesIEICE Transactions on Information and Systems, 2008
This paper is mainly concerned with a knowledge supply model in the environment of knowledge grid to realize the knowledge sharing globally. By integrating members, roles, and tasks in a workflow, three sorts of knowledge demands are gained. Based on knowledge demand information, a knowledge supply model is proposed for the purpose of delivering the ...
Lu Zhen, Zuhua Jiang
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

PARAMETRIC IDENTIFICATION IN KNOWLEDGE ESTIMATION MODELING

open access: yesВестник Российского экономического университета имени Г. В. Плеханова, 2017
The assessment of quality of training is the cornerstone of processes of stimulation of educational activity of the student, quality management of training, management of training as process of development of new knowledge etc.
Irina N. Maslyakova   +1 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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