Results 31 to 40 of about 3,293,562 (272)
ABSTRACT Background Families of children with cancer experience significant financial strain, even with universal healthcare. Indirect costs, such as productivity losses and non‐medical expenses, are rarely included in economic evaluations, and little is known about how effectively financial aid programmes alleviate this burden. Childhood brain tumours
Megumi Lim +8 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
Large Margin Nearest Neighbor Embedding for Knowledge Representation
Traditional way of storing facts in triplets ({\it head\_entity, relation, tail\_entity}), abbreviated as ({\it h, r, t}), makes the knowledge intuitively displayed and easily acquired by mankind, but hardly computed or even reasoned by AI machines ...
Fan, Miao +3 more
core +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Urban public transport is a very essential mode for urban residents’ commute travel; however, the unbalanced spatial and temporal distribution of travel demand usually leads to passenger flow congestion risk at certain section and time.
Siyong Ma +4 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Bio-Inspired Approaches to Safety and Security in IoT-Enabled Cyber-Physical Systems
Internet of Things (IoT) and Cyber-Physical Systems (CPS) have profoundly influenced the way individuals and enterprises interact with the world. Although attacks on IoT devices are becoming more commonplace, security metrics often focus on software ...
Anju P. Johnson +2 more
doaj +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
In supporting the implementation of ICT service management, Pusat Sistem Informasi dan Teknologi Keuangan (Pusintek) already have the Sistem Pengelolaan Layanan Teknologi Informasi dan Komunikasi (Sipelantik) application.
Andrianto Susilo +2 more
doaj +3 more sources

